CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

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Summary

In vivo as well as ex vivo genome editing using adeno-associated virus (AAV)-, lenti-virus-, or particle-mediated delivery of guide RNA in neurons, immune cells, and endothelial cells is demonstrated.

Type
article
Published
2014-09-01
Cited by
1,894
References
101
Access
Open access

Keywords

CRISPR, Biology, Cas9, Genome editing, Guide RNA

References

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