Multiple Sequence Alignment Using ClustalW and ClustalX
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Summary
The protocols in this unit discuss how to use ClustalX and ClUSTalW to construct an alignment, and create profile alignments by merging existing alignments.
- Type
- article
- Published
- 2003-01-01
- Cited by
- 2,969
- References
- 21
- OpenAlex
- https://openalex.org/W1515226261
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:34156490
Keywords
Computer science, Multiple sequence alignment, Unix, Sequence alignment, Graphical user interface
References
- Flexible sequence similarity searching with the FASTA3 program package.
- Using CLUSTAL for multiple sequence alignments.
- Of urfs and orfs : a primer on how to analyze devised amino acid sequences
- Profile analysis: detection of distantly related proteins.
- Multiple sequence alignment with Clustal X.
- Rapid similarity searches of nucleic acid and protein data banks.
- Improved Sensitivity of Nucleic Acid Database Searches Using Application-Specific Scoring Matrices
- CONFIDENCE LIMITS ON PHYLOGENIES: AN APPROACH USING THE BOOTSTRAP
- An improved algorithm for matching biological sequences.
- A general method applicable to the search for similarities in the amino acid sequence of two proteins.
- The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools.
- The neighbor-joining method: a new method for reconstructing phylogenetic trees.
- Twilight zone of protein sequence alignments.
- Fast and sensitive multiple sequence alignments on a microcomputer
- CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.
- Optimal alignments in linear space
- A comprehensive comparison of multiple sequence alignment programs
- CLUSTAL V: improved software for multiple sequence alignment
- CLUSTAL: a package for performing multiple sequence alignment on a microcomputer
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