Thon rings from amorphous ice and implications of beam-induced Brownian motion in single particle electron cryo-microscopy
Explore this paper's citation graph
Summary
Using the measured variation in the power spectra amplitude with number of electrons per image it is deduced that water molecules are randomly displaced by a mean squared distance of ∼1.1 ℬ2 for every incident 300 keV e−/Å2.
- Type
- article
- Published
- 2015-04-03
- Cited by
- 67
- References
- 19
- Access
- Open access
- OpenAlex
- https://openalex.org/W429513333
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9947708
Keywords
Brownian motion, Electron microscope, Amorphous solid, Particle (ecology), Cryo-electron microscopy
References
- High resolution electron microscopy
- The physical behavior of solid water at low temperatures and the embedding of electron microscopical specimens
- Electron microscopy of frozen water and aqueous solutions
- Correction of high-resolution data for curvature of the Ewald sphere.
- Detective Quantum Efficiency of Photodetectors with Some Amplification Mechanisms
- Über die von der molekularkinetischen Theorie der Wärme geforderte Bewegung von in ruhenden Flüssigkeiten suspendierten Teilchen [AdP 17, 549 (1905)]
- Transmission Electron Microscopy: A Textbook for Materials Science
- The Resolution Revolution
- Controlled environment vitrification system: an improved sample preparation technique.
- Accurate determination of local defocus and specimen tilt in electron microscopy.
- A Theory of Water and Ionic Solution, with Particular Reference to Hydrogen and Hydroxyl Ions
- Cryo-electron microscopy of vitrified specimens
- Comparison of optimal performance at 300 keV of three direct electron detectors for use in low dose electron microscopy
- Mathematical analysis of random noise
- Radiation damage in the TEM and SEM.
- The potential and limitations of neutrons, electrons and X-rays for atomic resolution microscopy of unstained biological molecules
- Observations on ice layers
- High-Resolution Electron Microscopy
Cited by
- Overview and future of single particle electron cryomicroscopy.
- CTFFIND4: Fast and accurate defocus estimation from electron micrographs
- Ultrastable gold substrates: Properties of a support for high-resolution electron cryomicroscopy of biological specimens
- A fast cross-validation method for alignment of electron tomography images based on Beer-Lambert law
- Progress towards an optimal specimen support for electron cryomicroscopy
- Specimen Behavior in the Electron Beam.
- Single particle electron cryomicroscopy: trends, issues and future perspective
- Using the Volta phase plate with defocus for cryo-EM single particle analysis
- Atomic insights into muscle contraction by transmission electron cryomicroscopy
- Robust image alignment for cryogenic transmission electron microscopy.
- Structural Study of Heterogeneous Biological Samples by Cryoelectron Microscopy and Image Processing
- Anomalous transport and diffusion of Brownian particles on disordered landscapes
- Detection of isolated protein-bound metal ions by single-particle cryo-STEM
- From Electron Crystallography to Single Particle CryoEM (Nobel Lecture).
- cisTEM: User-friendly software for single-particle image processing
- Orienting the future of bio-macromolecular electron microscopy
- Microscopic charge fluctuations cause minimal contrast loss in cryoEM
- cisTEM, user-friendly software for single-particle image processing
- Atomic resolution cryo-EM structure of β-galactosidase
- Pushing the resolution limit by correcting the Ewald sphere effect in single-particle Cryo-EM reconstructions
Related papers
- Cryo-electron microscopy of viruses
- Cryo-electron microscopy of vitreous sections of native biological cells and tissues.
- New Information from Large Tissue Volumes to the Smallest Structures of the Cell: What New Methods and Electron Microscopy Can Do for Your Research
- Let's Start Structural Analysis of Biomolecules with Cryo-Electron Microscopy
- Cryo-electron microscopy of insect flight muscle thick filaments. An approach to dynamic electron microscope studies.
- Fluorescent and Electron-Dense Green Color Emitting Nanodiamonds for Single-Cell Correlative Microscopy
- Hepatic changes produced by a single dose of endotoxin in the germfree mouse. Histochemistry, light microscopy, fluorescence microscopy, and electron microscopy.
- Rapid method for resectioning of light microscopy sections for electron microscopy
- Electron cryo-microscope -Where electron cryo-microscopy is and where it is going
- Correlated light and electron cryo-microscopy.