Increased CCL17 serum levels are associated with improved survival in advanced melanoma
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Summary
Serum levels of CCL17 and S100B represent independent prognostic markers for melanoma patients with distant metastases and were more powerful than the M category according to the AJCC classification to indicate overall survival.
- Type
- article
- Published
- 2015-05-20
- Cited by
- 18
- References
- 43
- Access
- Open access
- OpenAlex
- https://openalex.org/W305656793
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:756911
Keywords
Medicine, CCL17, Melanoma, Internal medicine, Oncology
References
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- Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans
- Malignant Melanoma S3‐Guideline “Diagnosis, Therapy and Follow‐up of Melanoma”
- Immature Dendritic Cells (DCs) Use Chemokines and Intercellular Adhesion Molecule (ICAM)-1, But Not DC-Specific ICAM-3-Grabbing Nonintegrin, to Stimulate CD4+ T Cells in the Absence of Exogenous Antigen1
- Serum S-100b protein as a prognostic marker in malignant cutaneous melanoma.
- High levels of serum HER-2/neu and YKL-40 independently reflect aggressiveness of metastatic breast cancer.
- YKL-40, a mammalian member of the chitinase family, is a matrix protein of specific granules in human neutrophils.
- Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell–licensed DCs
- Serum S100B, Lactate Dehydrogenase and Brain Metastasis Are Prognostic Factors in Patients with Distant Melanoma Metastasis and Systemic Therapy
- Serum markers lactate dehydrogenase and S100B predict independently disease outcome in melanoma patients with distant metastasis
- Long-Term Survival Analysis in Metastatic Melanoma: Serum S100B Is an Independent Prognostic Marker and Superior to LDH
- Comparative study of YKL-40, S-100B and LDH as monitoring tools for Stage IV melanoma.
- S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles.
- Prognostic factors in patients with metastatic malignant melanoma: A multivariate analysis
- NDR kinases regulate essential cell processes from yeast to humans
- The incidence and mortality of cutaneous melanoma in southern Germany
- High serum YKL-40 level in patients with small cell lung cancer is related to early death.
- An immune-active tumor microenvironment favors clinical response to ipilimumab
- TARC and RANTES enhance antitumor immunity induced by the GM-CSF-transduced tumor vaccine in a mouse tumor model
- Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages.
Cited by
- Low CCL-21 expression associates with unfavorable postoperative prognosis of patients with metastatic renal cell carcinoma
- Clinical Signifčcance of Serum Ykl-40 (Chitinase-3-Like-1 Protein) as a Biomarker in Melanoma: an Analysis of 112 Turkish Patients
- Immunological effect of local ablation combined with immunotherapy on solid malignancies
- Low CCL17 expression associates with unfavorable postoperative prognosis of patients with clear cell renal cell carcinoma
- Down-regulation of CCL17 in cancer-associated fibroblasts inhibits cell migration and invasion of breast cancer through ERK1/2 pathway
- Measured and genetically predicted plasma YKL-40 levels and melanoma mortality.
- Inhibition of melanoma by survivin-specific lymphocytes combined with CCL17 and granulocyte-macrophage colony-stimulating factor in a mouse syngeneic model.
- A Novel Signature of 23 Immunity-Related Gene Pairs Is Prognostic of Cutaneous Melanoma
- CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of the Ligands of Receptors CCR1, CCR2, CCR3, and CCR4
- CCR4 is a prognostic biomarker and correlated with immune infiltrates in head and neck squamous cell carcinoma
- Machine learning predicts cancer subtypes and progression from blood immune signatures
- Serum Proteomics in Patients with Head and Neck Cancer: Peripheral Blood Immune Response to Treatment
- Evolving polarisation of infiltrating and alveolar macrophages in the lung during metastatic progression of melanoma suggests CCR1 as a therapeutic target
- Transcriptomics of Canine Inflammatory Mammary Cancer Treated with Empty Cowpea Mosaic Virus Implicates Neutrophils in Anti-Tumor Immunity
- Subverting Attachment to Prevent Attacking: Alteration of Effector Immune Cell Migration and Adhesion as a Key Mechanism of Tumor Immune Evasion
- Circulating immune biomarkers correlating with response in patients with metastatic renal cell carcinoma on immunotherapy
- A Novel Signature of 23 Immunity-related Gene Pairs is Prognostic of Cutaneous Melanoma
- CMAR_A_211651 7439..7453
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