NDR kinases regulate essential cell processes from yeast to humans
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Summary
Combined data from yeast, worms, flies, mice and human cells now highlight the conserved and important roles of the different NDR kinases in distinct cellular processes.
- Type
- review
- Published
- 2006-04-01
- Cited by
- 349
- References
- 133
- OpenAlex
- https://openalex.org/W2012698880
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20717715
Keywords
Cytokinesis, Cell biology, Kinase, Biology, Mitosis
References
- The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis.
- Fission yeast MO25 protein is localized at SPB and septum and is essential for cell morphogenesis
- The growth regulators warts/lats and melted interact in a bistable loop to specify opposite fates in Drosophila R8 photoreceptors.
- Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product.
- The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition.
- Crystal structure of a human Mob1 protein: toward understanding Mob-regulated cell cycle pathways.
- MEN and SIN: what's the difference?
- Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction
- Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity
- cot‐1, a gene required for hyphal elongation in Neurospora crassa, encodes a protein kinase.
- Trypanosoma brucei MOB1 is required for accurate and efficient cytokinesis but not for exit from mitosis
- The budding yeast Dbf2 protein kinase localises to the centrosome and moves to the bud neck in late mitosis.
- Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase.
- Mosaic arrangement of ganglion cell receptive fields in rabbit retina.
- The tricornered gene, which is required for the integrity of epidermal cell extensions, encodes the Drosophila nuclear DBF2-related kinase.
- Lats2, a putative tumor suppressor, inhibits G1/S transition
- Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras.
- Drosophila Mob family proteins interact with the related tricornered (Trc) and warts (Wts) kinases.
- Phosphorylation and spindle pole body localization of the Cdc15p mitotic regulatory protein kinase in budding yeast.
- MST, a Physiological Caspase Substrate, Highly Sensitizes Apoptosis Both Upstream and Downstream of Caspase Activation*
Cited by
- Identification of a Novel Link between the Protein Kinase NDR1 and TGFβ Signaling in Epithelial Cells
- The Hippo pathway in disease and therapy: cancer and beyond
- SUMO‐specific protease 2 (SENP2) suppresses keratinocyte migration by targeting NDR1 for de‐SUMOylation
- Elucidation of the Multi-Faceted Roles of the SIN (Septation Initiation Network); Understanding How the SIN Promotes Cytokinesis and Inhibits Interphase Growth in the Fission Yeast Schizosaccharomyces pombe: A Dissertation
- Characterisation of the RAM pathway in Ustilago maydis
- Increased CCL17 serum levels are associated with improved survival in advanced melanoma
- dASPP and Boa regulate C-terminal Src kinase activity to control epithelial proliferation and integrity
- Understanding Regulation of the Cytoskeleton during Cell Cycle Transitions through Examination of Crosstalk between Homologous Fission Yeast Pathways, Septation Initiation Network and Morphogenesis ORB6 Network: A Dissertation
- NDR Kinases Are Essential for Somitogenesis and Cardiac Looping during Mouse Embryonic Development
- Lower Levels of Human MOB3B Are Associated with Prostate Cancer Susceptibility and Aggressive Clinicopathological Characteristics
- Analysis of the architecture and function of the nuclear DNA replication apparatus in Trypanosoma brucei
- Mammalian NDR kinases : tumor suppressors with essential functions in embryonic development
- Characterization and Evolution of the Cell Cycle-Associated Mob Domain-Containing Proteins in Eukaryotes
- Substrate Analysis of the Pneumocystis carinii Protein Kinases PcCbk1 and PcSte20 Using Yeast Proteome Microarrays Provides a Novel Method for Pneumocystis Signaling Biology.
- Canine Models of Human Vision Disorders: Identification of New Loci and Genes for Glaucoma and Retinal Degeneration
- Phospho-regulation of Lrg1 controls polarised growth in the human fungal pathogen Candida albicans
- Epidemiological approaches to understanding complex diseases: Applications in congenital heart disease and cancer
- Investigating the role of intra- and extra-cellular modulators of the transcription factor NF-kappaB
- NDR1/STK38 potentiates NF‐κB activation by its kinase activity
- Cellular and molecular analysis of NDR and LATS kinases in dictyostelium
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