Oral Solid Controlled Release Dosage Forms: Role of GI-Mechanical Destructive Forces and Colonic Release in Drug Absorption Under Fasted and Fed Conditions in Humans
Explore this paper's citation graph
Summary
Effects of GI destructive forces on the tablet erosion and the release inhibition in the colon must be considered in the development of CR dosage forms.
- Type
- article
- Published
- 1995-07-01
- Cited by
- 65
- References
- 17
- OpenAlex
- https://openalex.org/W304527029
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:38662656
Keywords
In vivo, Dosage form, Chemistry, Liberation, Dissolution
References
- Bioavailability of nalidixic acid from uncoated tablets in humans--Part I: Correlation with the dissolution rates of the tablets.
- Theophylline-Controlled Release Preparations and Fatty Food: An in Vitro Study Using the Rotating Dialysis Cell Method
- Release and Absorption Characteristics of Novel Theophylline Sustained-Release Formulations: In Vitro-in Vivo Correlation
- Absorption, Gastrointestinal Transit, and Tablet Erosion of Felodipine Extended-Release (ER) Tablets
- Estimation of Agitation Intensity in the GI Tract in Humans and Dogs Based on in Vitro/in Vivo Correlation
- Determination of the mechanical impact force in the in vitro dissolution test and evaluation of the correlation between in vivo and in vitro release
- Bioavailability from felodipine extended-release tablets with different dissolution properties
- Predictive modelling of the behaviour of a controlled release buflomedil HC1 formulation using scintigraphic and pharmacokinetic data
- Bimodal release of ibuprofen in a sustained-release formulation: a scintigraphic and pharmacokinetic open study in healthy volunteers under different conditions of food intake
- An inequality-constrained least-squares deconvolution method
- A comparative study of saliva and serum paracetamol levels using a simple spectrophotometric method.
- Drug absorption from large intestine: physicochemical factors governing drug absorption.
- Dissolution systems for chloramphenicol tablet bioavailability.
- Transit of pharmaceutical dosage forms through the small intestine.
- A pharmacokinetic analysis program (multi) for microcomputer.
- Effect of food on bioavailability of metronidazole from sugar-coated tablets having different dissolution rates in subjects with low gastric acidity.
- Feasibility of in-vitro/in-vivo correlation in the case of a new sustained-release theophylline pellet formulation.
Cited by
- In vivo drug release from hydrophilic dextran tablets capable of forming polyion complex.
- Synchronized Release of Sulpiride and Sodium Decanoate from HPMC Matrices: A Rational Approach to Enhance Sulpiride Absorption in the Rat Intestine
- Colon-Targeted Oral Drug Delivery Systems: Design Trends and Approaches
- Gastrointestinal Drug Absorption: Is It Time to Consider Heterogeneity as Well as Homogeneity?
- Effect of Destruction Force on Drug Release from Multiple Unit Controlled Release Dosage Forms in Humans
- Dissolution testing of oral modified‐release dosage forms
- Formulation development strategies for oral extended release dosage form
- New oral delivery systems for treatment of inflammatory bowel disease.
- Bolus Formation and Disintegration during Digestion of Food Carbohydrates
- Hydrodynamic Flows Around Tablets in Different Pharmacopeial Dissolution Tests
- Development of an oral sustained release drug delivery system utilizing pH-dependent swelling of carboxyvinyl polymer.
- Release-controlling absorption enhancement of enterally administered Ophiopogon japonicus polysaccharide by sodium caprate in rats.
- Formulation variation and in vitro-in vivo correlation for a rapidly swellable three-layered tablet of tamsulosin HCl.
- Floating matrix dosage form for phenoporlamine hydrochloride based on gas forming agent: in vitro and in vivo evaluation in healthy volunteers.
- Solubility Enhancement of Budesonide and Statistical Optimization of Coating Variables for Targeted Drug Delivery
- In vitro and in vivo evaluation of a matrix-in-cylinder system for sustained drug delivery.
- Prediction of in vivo drug release behavior of controlled-release multiple-unit dosage forms in dogs using a flow-through type dissolution test method.
- The effect of polyion complex formation on in vitro/in vivo correlation of hydrophilic matrix tablets.
- Significance of lipid matrix aging on in vitro release and in vivo bioavailability.
- Biopharmaceutical considerations and characterizations in development of colon targeted dosage forms for inflammatory bowel disease
Related papers
- Liberation of lithium from sustained release preparations. A comparison of seven registered brands.
- Dissolution testing for sustained or controlled release oral dosage forms and correlation with in vivo data: Challenges and opportunities
- A REVIEW ON FORMULATION APPROACHES IN IMMEDIATE RELEASE TABLET
- Individual Oral Therapy with Immediate Release and Effervescent Formulations Delivered by the Solid Dosage Pen
- A REVIEW ON IMMEDIATE RELEASE DRUG DELIVERY SYSTEM
- [Oral controlled release dosage forms].