The FcRgamma chain is not essential for induction of experimental allergic encephalomyelitis (EAE) or anti-myelin antibody-mediated exacerbation of EAE.

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Summary

The role of FcgammaR and anti-myelin antibodies in MOG35-55-induced experimental allergic encephalomyelitis (EAE) in C57BL/6 mice is studied, demonstrating that the FcRy chain is not essential for induction of EAE, but that FcRgamma signaling may contribute to the preclinical phase.

Type
article
Published
2005-04-01
Cited by
16
References
68
Access
Open access

Keywords

Experimental autoimmune encephalomyelitis, Immunology, Proteolipid protein 1, Antibody, Myelin

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