Activation of SAPK/JNKs in vitro.

Keywords

Cell biology, Kinase, p38 mitogen-activated protein kinases, MAP kinase kinase kinase, Mitogen-activated protein kinase

References

• Scaffold proteins in mammalian MAP kinase cascades.Juan Antonio Herrero Brasas — 2004
• The stress-activated protein kinases are major c-Jun amino-terminal kinases activated by ischemia and reperfusion.Celia M. Pombo, Joseph V. Bonventre, Joseph Avruch — 1994
• JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain.Benoit Dérijard, Masahiko Hibi, I‐Huan Wu — 1994
• Evidence for a Role of Rho-like GTPases and Stress-activated Protein Kinase/c-Jun N-terminal Kinase (SAPK/JNK) in Transforming Growth Factor β-mediated Signaling*Azeddine Atfi, Siham Djelloul, Eric Chastre — 1997
• Secondary and Tertiary Structure Changes of Reconstituted P-glycoproteinNathalie Sonveaux, Adam B. Shapiro, Erik Goormaghtigh — 1996
• Activation of p38 Mitogen-activated Protein Kinase by c-Abl-dependent and -independent Mechanisms*Pramod S. Pandey, Joël Raingeaud, Masao Kaneki — 1996
• Induction of Apoptosis by DPC4, a Transcriptional Factor Regulated by Transforming Growth Factor-β through Stress-activated Protein Kinase/c-Jun N-terminal Kinase (SAPK/JNK) Signaling Pathway*Azeddine Atfi, Maud Buisine, Anne Mazars — 1997
• The stress-activated protein kinase subfamily of c-Jun kinasesJohn Kyriakis, Papia T. Banerjee, Eleni Nikolakaki — 1994
• An osmosensing signal transduction pathway in mammalian cells.Zoya Galcheva-Gargova, Benoît Dérijard, I‐Huan Wu — 1994
• GCK is essential to systemic inflammation and pattern recognition receptor signaling to JNK and p38J. Zhong, L. Gavrilescu, Á. Molnár — 2009
• Gene 33/Mig-6, a Transcriptionally Inducible Adapter Protein That Binds GTP-Cdc42 and Activates SAPK/JNK*Anthony Makkinje, Deborah A. Quinn, Ang Chen — 2000
• Sounding the Alarm: Protein Kinase Cascades Activated by Stress and Inflammation*John Kyriakis, Joseph Avruch — 1996
• The Seven-transmembrane-spanning Receptors for Endothelin and Thrombin Cause Proliferation of Airway Smooth Muscle Cells and Activation of the Extracellular Regulated Kinase and c-Jun NH-terminal Kinase Groups of Mitogen-activated Protein Kinases (*)Paul Shapiro, John N. Evans, Roger J. Davis — 1996
• Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.Masahiko Hibi, Anning Lin, Tod Smeal — 1993
• JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosisKui Lei, Roger J. Davis — 2003
• MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferationDeborah Chadee, John Kyriakis — 2004
• Dissection of a Signaling Pathway by Which Pathogen-associated Molecular Patterns Recruit the JNK and p38 MAPKs and Trigger Cytokine Release*Jian Zhong, John Kyriakis — 2007
• Germinal Center Kinase Is Required for Optimal Jun N-Terminal Kinase Activation by Toll-Like Receptor Agonists and Is Regulated by the Ubiquitin Proteasome System and Agonist-Induced, TRAF6-Dependent StabilizationJian Zhong, John Kyriakis — 2004
• Regulation of MAP kinase signaling modules by scaffold proteins in mammals.Deborah K. Morrison, Roger J. Davis — 2003
• Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation.John Kyriakis, Joseph Avruch — 2001

Cited by

• miR-92a inhibits vascular smooth muscle cell apoptosis: role of the MKK4–JNK pathwayLan Zhang, Mi Zhou, Yingjie Wang — 2014
• The protective effect of 17β-estradiol against hydrogen peroxide-induced apoptosis on mesenchymal stem cell.Haiying Chen, Xian Zhang, Shuangfeng Chen — 2012
• Building on the foundation of daring hypotheses: Using the MKK4 metastasis suppressor to develop models of dormancy and metastatic colonizationMatthew T. Knopeke, Eric T. Ritschdorff, R. J. H. Clark — 2011
• DGCR8 mediates repair of UV-induced DNA damage independently of RNA processingPhilamer Calses, Kiranjit K. Dhillon, Nyka Tucker — 2017
• PlMAPK10, a Mitogen-Activated Protein Kinase (MAPK) in Peronophythora litchii, Is Required for Mycelial Growth, Sporulation, Laccase Activity, and Plant InfectionLiqun Jiang, Junjian Situ, Yizhen Deng — 2018
• The JNK Signaling Pathway in Inflammatory Skin Disorders and CancerM. Ben Hammouda, Amy E. Ford, Yuan Liu — 2020
• Human Papillomavirus and Cellular Pathways: Hits and TargetsAlessandro Medda, Daria Duca, Susanna Chiocca — 2021
• The Hallmarks of Flavonoids in CancerLuis Gustavo Saboia Ponte, Isadora Carolina Betim Pavan, Mariana Camargo Silva Mancini — 2021
• The Roles of c-Jun N-Terminal Kinase (JNK) in Infectious DiseasesJing Chen, Chao Ye, Chao Wan — 2021
• Circ_0084043-miR-134-5p axis regulates PCDH9 to suppress melanomaGui-Yue Cai, Ruitao Zou, Hui-Zhi Yang — 2022
• Regulation of the microglial polarization for alleviating neuroinflammation in the pathogenesis and therapeutics of major depressive disorder.Yufei Wang, Cong-Ya Chen, Lan Lei — 2025
• PALACKY UNIVERSITY OLOMOUC Faculty of Natural Sciences Department of Biochemistry The effect of graphene oxide on the pregnane X receptor signaling pathway regulating the biotransformation of xenobioticsD. Thesis, Irena Malichová — 2017

Related papers

• A mammalian scaffold complex that selectively mediates MAP kinase activation.Alan J. Whitmarsh, Julie Cavanagh, Cathy Tournier — 1998
• Purification of a 12,020-Dalton Protein That Enhances the Activation of Mitogen-activated Protein (MAP) Kinase by MAP Kinase Kinase (*)Anisa Scott, Clare M.M. Haystead, Timothy Haystead — 1995
• Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoformsBenoît Dérijard, Joël Raingeaud, Tamera Barrett — 1995
• A Novel Tobacco Mitogen-activated Protein (MAP) Kinase Kinase, NtMEK1, Activates the Cell Cycle-regulated p43Ntf6 MAP Kinase*Ornella Calderini, Nathalie Glab, Catherine Bergounioux — 2001
• The Plant Mitogen-activated Protein (MAP) KinaseQiang Liu, Guiyou Zhang, Kazuo Shinozaki — 2000
• Feedback Regulation of Raf-1 and Mitogen-activated Protein Kinase (MAP) Kinase Kinases 1 and 2 by MAP Kinase Phosphatase-1 (MKP-1)*Paul Shapiro, Natalie G. Ahn — 1998
• Evidence that inactive p42 mitogen-activated protein kinase and inactive Rsk exist as a heterodimer in vivo.Kuang‐Ming Hsiao, S Y Chou, S J Shih — 1994
• Activation of a p38 mitogen-activated protein kinase in human neutrophils by lipopolysaccharide.Jerry A. Nick, Natalie J. Avdi, Pär Gerwins — 1996
• Constitutive activation of mitogen-activated protein kinase pathway in acute leukemia cellsMasayuki Towatari, Hiroatsu Iida, Mitsune Tanimoto — 1997