Scaffold proteins in mammalian MAP kinase cascades.
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Summary
Recent advances in the study of potential mammalian scaffold proteins that may help to understand the complex regulation, including the spatial and temporal control, of the mammalian MAPK signaling pathways are described.
- Type
- article
- Published
- 2004-06-01
- Cited by
- 77
- References
- 54
- Access
- Open access
- OpenAlex
- https://openalex.org/W15213240
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:42264943
Keywords
Minor (academic), Political science, Philosophy, Humanities
References
- Phosphorylation-dependent Scaffolding Role of JSAP1/JIP3 in the ASK1-JNK Signaling Pathway
- Mitogen-Activated Protein Kinases: Specific Messages from Ubiquitous Messengers
- KSR: a MAPK scaffold of the Ras pathway?
- The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals.
- A mammalian scaffold complex that selectively mediates MAP kinase activation.
- In Vitro Development of Mouse Embryonic Stem Cells Lacking JNK/Stress-activated Protein Kinase-associated Protein 1 (JSAP1) Scaffold Protein Revealed Its Requirement during Early Embryonic Neurogenesis*
- From receptors to stress-activated MAP kinases
- cDNA cloning and mapping of a novel islet-brain/JNK-interacting protein.
- A β-Arrestin-dependent Scaffold Is Associated with Prolonged MAPK Activation in Pseudopodia during Protease-activated Receptor-2-induced Chemotaxis*
- Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction.
- Mammalian MAP kinase signalling cascades
- JLP: A scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors
- Expression of JNK cascade scaffold protein JSAP1 in the mouse nervous system.
- A Scaffold Protein in the c-Jun NH2-terminal Kinase Signaling Pathways Suppresses the Extracellular Signal-regulated Kinase Signaling Pathways*
- Islet-Brain1/JNK-interacting Protein-1 Is Required for Early Embryogenesis in Mice*
- β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
- The JNK-interacting Protein-1 Scaffold Protein Targets MAPK Phosphatase-7 to Dephosphorylate JNK*
- Scaffold Role of a Mitogen-activated Protein Kinase Phosphatase, SKRP1, for the JNK Signaling Pathway*
- Recruitment of JNK to JIP1 and JNK-dependent JIP1 Phosphorylation Regulates JNK Module Dynamics and Activation*
- Fibroblast Growth Factor Homologous Factors and the Islet Brain-2 Scaffold Protein Regulate Activation of a Stress-activated Protein Kinase*
Cited by
- Activation of SAPK/JNKs in vitro.
- The Role of ERK5 in Cell Proliferation
- Neural-specific ablation of the scaffold protein JSAP1 in mice causes neonatal death.
- Impairment of cardiomyogenesis in embryonic stem cells lacking scaffold protein JSAP1.
- TAB2, a nucleoside diphosphate protein kinase, is a component of the tMEK2 disease resistance pathway in tomato
- The modulation of tumour suppressor MST2 and proto-oncogene Raf-1 kinases by the scaffold protein CNK1
- Role of plasma membrane localization of the scaffold protein JSAP1 during differentiation of cerebellar granule cell precursors
- IgA1 immune complex-mediated activation of MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathy
- ROS mediated MAPK signaling in abiotic and biotic stress- striking similarities and differences
- Critical role of JSAP1 and JLP in axonal transport in the cerebellar Purkinje cells of mice
- Phosphorylation‐dependent binding of human transcription factor MOK2 to lamin A/C
- Extracellular signal-regulated kinase regulates clathrin-independent endosomal trafficking.
- The scaffold protein JLP plays a key role in regulating ultraviolet B‐induced apoptosis in mice
- Reassembly of JIP1 Scaffold Complex in JNK MAP Kinase Pathway Using Heterologous Protein Interactions
- Bilberry-Derived Anthocyanins Prevent IFN-γ-Induced Pro-Inflammatory Signalling and Cytokine Secretion in Human THP-1 Monocytic Cells
- Functional effects of protein kinases and peroxynitrite on cardiac carnitine palmitoyltransferase-1 in isolated mitochondria
- Regulation of N-cadherin-based cell-cell interaction by JSAP1 scaffold in PC12h cells.
- Knockdown of Sec8 enhances the binding affinity of c‐Jun N‐terminal kinase (JNK)‐interacting protein 4 for mitogen‐activated protein kinase kinase 4 (MKK4) and suppresses the phosphorylation of MKK4, p38, and JNK, thereby inhibiting apoptosis
- The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions
- Non-visual arrestins function as simple scaffolds assembling the MKK4–JNK3a2 signaling complex
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