Metabolic signals and innate immune activation in obesity and exercise.
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Summary
Current knowledge of the cellular recognition mechanisms for FFAs, theinflammatory signaling pathways triggered by excess FFAs in obesity and the counteractive effects of both acute and chronic exercise on obesity-induced activation of inflammatory signaling pathways are summarized.
- Type
- article
- Published
- 2015-01-01
- Cited by
- 122
- References
- 114
- OpenAlex
- https://openalex.org/W101189329
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19886970
Keywords
Inflammasome, Inflammation, Insulin resistance, Medicine, Innate immune system
References
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Cited by
- Oxidative Stress, Disrupted Energy Metabolism, and Altered Signaling Pathways in Glutaryl-CoA Dehydrogenase Knockout Mice: Potential Implications of Quinolinic Acid Toxicity in the Neuropathology of Glutaric Acidemia Type I
- Ginsenoside Rb1 and compound K improve insulin signaling and inhibit ER stress-associated NLRP3 inflammasome activation in adipose tissue
- Metabolic syndrome, atherosclerosis and inflammation: an inseparable triad?
- Oxidative aspects of metabolic syndrome and atherosclerosis
- Molecular physiopathology of obesity-related diseases: multi-organ integration by GRK2
- Obesity Impacts Fever and Sickness Behavior During Acute Systemic Inflammation.
- Tratamento com metformina restaurou danos metabólicos causados pela obesidade, mas induziu a resposta inflamatória hepática
- Adaptação Cultural e Validação do Questionário: “Pregnancy Physical Activity Questionnaire” para a População Portuguesa
- Influence of Acute and Chronic Exercise on Glucose Uptake
- Skeletal Muscle Insulin Resistance and Absence of Inflammation Characterize Insulin-Resistant Grade I Obese Women
- Different effects of strength and endurance exercise training on COX-2 and mPGES expression in mouse brain are independent of peripheral inflammation.
- Well-being and immune response: a multi-system perspective.
- INTENSIDADE DE EXERCÍCIO FÍSICO E IMUNOMODULAÇÃO: IMPACTOS EM INFECÇÕES DAS VIAS AÉREAS
- Physical exercise alleviates ER stress in obese humans through reduction in the expression and release of GRP78 chaperone.
- Healthy overweight/obese youth: early osteosarcopenic obesity features
- Exercise Affects T-Cell Function by Modifying Intracellular Calcium Homeostasis
- Exercise-Induced Release of Pharmacologically Active Substances and Their Relevance for Therapy of Hepatic Injury
- Exercise Does Not Protect against Peripheral and Central Effects of a High Cholesterol Diet Given Ad libitum in Old ApoE−/− Mice
- Impact of resistance training on the autophagy-inflammation-apoptosis crosstalk in elderly subjects
- Mangiferin suppresses endoplasmic reticulum stress in perivascular adipose tissue and prevents insulin resistance in the endothelium
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