Tumor dormancy: long-term survival in a hostile environment.
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Summary
Elucidating the mechanisms underlying the equilibrium that allows for the persistence of dormant tumor cells presents a novel strategy for targeted drug treatment in the context of maintenance therapy.
- Type
- article
- Published
- 2013-01-01
- Cited by
- 21
- References
- 80
- OpenAlex
- https://openalex.org/W80575831
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:31999310
Keywords
Cytotoxic T cell, Cancer research, Immune system, Autocrine signalling, Cancer cell
References
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- Tumor dormancy and cell signaling: anti-mu-induced apoptosis in human B-lymphoma cells is not caused by an APO-1-APO-1 ligand interaction.
- Molecular persistence of chronic myeloid leukemia caused by donor T cells specific for lineage-restricted maturation antigens not recognizing immature progenitor-cells
- Tumor dormancy and immunoescape
- Indoleamine 2,3-dioxygenase activity of acute myeloid leukemia cells can be measured from patients' sera by HPLC and is inducible by IFN-gamma.
- BCR-ABL kinase is dead; long live the CML stem cell.
Cited by
- L'hypoxie contribue à la quiescence et la chimiorésistance des cellules initiatrices de leucémie aigüe lymphoblastique
- Chemoquiescence for Ideal Cancer Treatment and Prevention: Where Are We Now?
- Crosstalk between DNA repair and cancer stem cell (CSC) associated intracellular pathways.
- Mathematical models of immune-induced cancer dormancy and the emergence of immune evasion
- CLINICAL EFFECTS OF BLOOD TRANSFUSION IN ESOPHAGEAL SURGERY
- Melanoma dormancy in a mouse model is linked to GILZ/FOXO3A-dependent quiescence of disseminated stem-like cells
- Dissect the Dynamic Molecular Circuits of Cell Cycle Control through Network Evolution Model
- A Change of Treatment Strategy against Cancer: Can Cancer be Controlled rather than Cured?
- Role of the microenvironment in maintenance and resistance of leukemic stem cells in Chronic Myelogenous Leukemia. BMP pathway and mechanical forces
- Non-Cell Autonomous Effects of the Senescence-Associated Secretory Phenotype in Cancer Therapy
- Assessing stemness and proliferation properties of the newly established colon cancer 'stem' cell line, CSC480 and novel approaches to identify dormant cancer cells.
- Rôle de la protéine immuno-régulatrice PD-L1 sur le métabolisme des cellules tumorales
- PHLDB2 Mediates Cetuximab Resistance via Interacting With EGFR in Latent Metastasis of Colorectal Cancer
- The covert symphony: cellular and molecular accomplices in breast cancer metastasis
- Deciphering genetic and nongenetic factors underlying tumour dormancy: insights from multiomics analysis of two syngeneic MRD models of melanoma and leukemia
- Navigating the Complexity of Resistance in Lung Cancer Therapy: Mechanisms, Organoid Models, and Strategies for Overcoming Treatment Failure
- Defeating lethal cancer: Interrupting the ecologic and evolutionary basis of death from malignancy
- Nano-biomaterials in cancer therapy: Advances in targeting and overcoming cancer stem cell resistance
- Additional file 2 of Deciphering genetic and nongenetic factors underlying tumour dormancy: insights from multiomics analysis of two syngeneic MRD models of melanoma and leukemia
- Additional file 2 of Deciphering genetic and nongenetic factors underlying tumour dormancy: insights from multiomics analysis of two syngeneic MRD models of melanoma and leukemia
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