REPSA: combinatorial approach for identifying preferred drug-DNA binding sequences.

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Summary

Restriction Endonuclease Protection Selection and Amplification (REPSA) is a powerful, versatile, general method for the combinatorial determination of small molecule-DNA binding specificity and a functional means for drug discovery and characterization.

Type
article
Published
2010-01-01
Cited by
4
References
16

Keywords

DNA, Small molecule, DNA binding site, Computational biology, Netropsin

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