REPSA: combinatorial approach for identifying preferred drug-DNA binding sequences.
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Summary
Restriction Endonuclease Protection Selection and Amplification (REPSA) is a powerful, versatile, general method for the combinatorial determination of small molecule-DNA binding specificity and a functional means for drug discovery and characterization.
- Type
- article
- Published
- 2010-01-01
- Cited by
- 4
- References
- 16
- OpenAlex
- https://openalex.org/W47637412
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2313298
Keywords
DNA, Small molecule, DNA binding site, Computational biology, Netropsin
References
- Molecular Aspects of Anticancer Drug/DNA Interactions
- Fitting a Mixture Model By Expectation Maximization To Discover Motifs In Biopolymer
- Identification of preferred hTBP DNA binding sites by the combinatorial method REPSA.
- Identification of preferred actinomycin-DNA binding sites by the combinatorial method REPSA.
- Exploring molecular diversity with combinatorial shape libraries.
- CASTing for multicomponent DNA-binding complexes.
- In vitro genetics.
- Molecular recognition of DNA by small molecules.
- Class-IIS restriction enzymes--a review.
- Sequence specificity of triplex DNA formation: Analysis by a combinatorial approach, restriction endonuclease protection selection and amplification.
- Identification of preferred distamycin-DNA binding sites by the combinatorial method REPSA.
- Combinatorial identification of a novel consensus sequence for the covalent DNA-binding polyamide tallimustine.
- Diversity of oligonucleotide functions.
- In vitro selection of functional nucleic acids.
- Proceedings: Second international conference on intelligent systems for molecular biology
Cited by
- Anti- Japanese-Encephalitis-Viral Effects of Kaempferol and Daidzin and Their RNA-Binding Characteristics
- Recent advances in predicting protein classification and their applications to drug development.
- Drug target identification in protozoan parasites
- Using Restriction Endonuclease, Protection, Selection, and Amplification to Identify Preferred DNA-Binding Sequences of Microbial Transcription Factors
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