High levels of human apolipoprotein A-I and high density lipoproteins in transgenic mice do not enhance efflux of cholesterol from a depot of injected lipoproteins. Relevance to regression of atherosclerosis?

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Summary

It appears, therefore, that while an increase above physiological levels of apo A-I or plasma HDL does play a pivotal role in the prevention of initiation and progression of early stages of atherosclerosis, the effectiveness of such an increase for the regression stage remains still to be demonstrated.

Type
article
Published
1999-06-01
Cited by
22
References
45

Keywords

Cholesterol, Endocrinology, Apolipoprotein B, Internal medicine, Efflux

References

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