Identification of Scavenger Receptor SR-BI as a High Density Lipoprotein Receptor
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Summary
It is shown that the class B scavenger receptor SR-BI is an HDL receptor, which mediates selective cholesterol uptake by a mechanism distinct from the classic LDL receptor pathway.
- Type
- article
- Published
- 1996-01-26
- Cited by
- 2,440
- References
- 40
- OpenAlex
- https://openalex.org/W1985170971
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:249922
Keywords
Scavenger receptor, Receptor, Catabolism, LDL receptor, Lipoprotein
References
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- Uptake of high-density lipoprotein-associated apoprotein A-I and cholesterol esters by 16 tissues of the rat in vivo and by adrenal cells and hepatocytes in vitro.
- Expression cloning of SR-BI, a CD36-related class B scavenger receptor.
- Rat adrenal uptake and metabolism of high density lipoprotein cholesteryl ester.
- Identification, primary structure, and distribution of CLA-1, a novel member of the CD36/LIMPII gene family.
- Cholesterol uptake by the 'selective' pathway of ovarian granulosa cells: early intracellular events.
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- The role of apolipoproteins of HDL in the selective uptake of cholesteryl linoleyl ether by cultured rat and bovine adrenal cells.
- Dissection of compartments in rat hepatocytes involved in the intracellular trafficking of high‐density lipoprotein particles or their selectively internalized cholesteryl esters
- The uptake of the apoprotein and cholesteryl ester of high-density lipoproteins by the perfused rat liver.
- Defining lipid transport pathways in animal cells.
- Metabolism of HDL-cholesteryl ester in the rat, studied with a nonhydrolyzable analog, cholesteryl linoleyl ether.
- The Class B Scavenger Receptors SR-BI and CD36 Are Receptors for Anionic Phospholipids (*)
- The role of lipoproteins in steroidogenesis and cholesterol metabolism in steroidogenic glands.
- Reconstituted low density lipoprotein: a vehicle for the delivery of hydrophobic fluorescent probes to cells.
- Cholesterol transport between cells and high-density lipoproteins.
Cited by
- Heteronuclear NMR studies of human serum apolipoprotein A‐I
- Microglial Cells Internalize Aggregates of the Alzheimer's Disease Amyloid β-Protein Via a Scavenger Receptor
- Human cytomegalovirus increases modified low density lipoprotein uptake and scavenger receptor mRNA expression in vascular smooth muscle cells.
- Heparan Sulfate Proteoglycans Participate in Hepatic Lipaseand Apolipoprotein E-mediated Binding and Uptake of Plasma Lipoproteins, Including High Density Lipoproteins*
- Delayed increase in high density lipoprotein-phospholipids after ingestion of a fat load in normolipidemic patients with coronary artery disease.
- Thyroid hormone efflux from monolayer cultures of human fibroblasts and hepatocytes. Effect of lipoproteins and other thyroxine transport proteins.
- Comparison of expression and regulation of the high-density lipoprotein receptor SR-BI and the low-density lipoprotein receptor in human adrenocortical carcinoma NCI-H295 cells.
- Alpha-tocopherol metabolism is abnormal in scavenger receptor class B type I (SR-BI)-deficient mice.
- Dietary myristic acid modifies the HDL-cholesterol concentration and liver scavenger receptor BI expression in the hamster.
- Scavenger receptor class BI and selective cholesteryl ester uptake: partners in the regulation of steroidogenesis.
- The Recycling of Apolipoprotein E in Primary Cultures of Mouse Hepatocytes
- Association Between a Novel 11–Base Pair Deletion Mutation in the Promoter Region of the Scavenger Receptor Class B Type I Gene and Plasma HDL Cholesterol Levels in Taiwanese Chinese
- Lipoprotein disorders and cardiovascular risk
- Quantification of apolipoprotein E receptors in human brain-derived cell lines by real-time polymerase chain reaction.
- Biliary lipid secretion.
- Apolipoprotein A-I but not high-density lipoproteins are internalised by RAW macrophages: roles of ATP-binding cassette transporter A1 and scavenger receptor BI
- Reconstituted high-density lipoprotein attenuates postinfarction left ventricular remodeling in rats.
- Hepatitis C Virus entry: the early steps in the viral replication cycle
- Signal transduction pathways provide opportunities to enhance HDL and apoAI-dependent reverse cholesterol transport.
- Mechanisms regulating hepatic SR-BI expression and their impact on HDL metabolism.
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