Reverse cholesterol transport--a review of the process and its clinical implications.
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Summary
The development of techniques to identify and characterize the functional significance of mutations in proteins involved in RCT will aid in the understanding of the mechanisms and control of this pathway.
- Type
- article
- Published
- 1997-10-01
- Cited by
- 138
- References
- 74
- OpenAlex
- https://openalex.org/W2015293456
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:36986554
Keywords
Reverse cholesterol transport, Cholesterylester transfer protein, Cholesterol, ABCA1, Internal medicine
References
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- The Metabolic basis of inherited disease
- Inhibition of the cellular secretion of cholesteryl ester transfer protein by a variant protein formed by alternative splicing of mRNA.
- Mammalian adipose tissue and muscle are major sources of lipid transfer protein mRNA.
- Interaction of high density lipoprotein with its receptor on cultured fibroblasts and macrophages. Evidence for reversible binding at the cell surface without internalization.
- Monoclonal antibodies to the Mr 74,000 cholesteryl ester transfer protein neutralize all of the cholesteryl ester and triglyceride transfer activities in human plasma.
- Human hepatic triglyceride lipase expression reduces high density lipoprotein and aortic cholesterol in cholesterol-fed transgenic mice.
- Hepatic lipase induces the formation of pre-beta 1 high density lipoprotein (HDL) from triacylglycerol-rich HDL2. A study comparing liver perfusion to in vitro incubation with lipases.
- Distribution and functions of lecithin:cholesterol acyltransferase and cholesteryl ester transfer protein in plasma lipoproteins. Evidence for a functional unit containing these activities together with apolipoproteins A-I and D that catalyzes the esterification and transfer of cell-derived choleste
- The CCAAT/enhancer-binding protein trans-activates the human cholesteryl ester transfer protein gene promoter.
- Identification and characterization of a high density lipoprotein-binding protein in cell membranes by ligand blotting.
- A compound heterozygote for hepatic lipase gene mutations Leu334-->Phe and Thr383-->Met: correlation between hepatic lipase activity and phenotypic expression.
- Libyan family with hypercholesterolemia and increased high-density lipoprotein cholesterol in plasma.
- Increased Lipid Transfer Activities in Hyperlipidemic Rabbit Plasma
- Molecular physiology of reverse cholesterol transport.
- Human ApoA-II inhibits the hydrolysis of HDL triglyceride and the decrease of HDL size induced by hypertriglyceridemia and cholesteryl ester transfer protein in transgenic mice.
- Regulation of cholesteryl ester transfer protein (CETP) activity: review of in vitro and in vivo studies.
- Overexpression of hepatic lipase in transgenic rabbits leads to a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins.
Cited by
- Controversy on high density lipoprotein raising therapy.
- Apolipoprotein A-I: Insights from Redox Proteomics for its Role in Neurodegeneration
- High levels of human apolipoprotein A-I and high density lipoproteins in transgenic mice do not enhance efflux of cholesterol from a depot of injected lipoproteins. Relevance to regression of atherosclerosis?
- Arachidonate Remodeling and Inflammation
- DOXORUBICIN-INDUCED, TNF-α-MEDIATED BRAIN OXIDATIVE STRESS, NEUROCHEMICAL ALTERATIONS, AND COGNITIVE DECLINE: INSIGHTS INTO MECHANISMS OF CHEMOTHERAPY INDUCED COGNITIVE IMPAIRMENT AND ITS PREVENTION
- Measuring insulin sensitivity and the effect of alternative dietary interventions and exercise on metabolic control
- Genetic Variation of Apolipoprotein B in the Finns: Effects of Serum Lipid Levels
- Cholesterol Binding Activity of ApoAI Mimetic Peptide L4F
- Expression of cholesteryl ester transfer protein in human atherosclerotic lesions and its implication in reverse cholesterol transport.
- The Regulation of Reverse Cholesterol Transport and Cellular Cholesterol Homeostasis by MicroRNAs
- Potential peptides in atherosclerosis therapy.
- A common mutation in cholesteryl ester transfer protein gene and plasma HDL cholesterol level before and after hormone replacement therapy in Korean postmenopausal women
- Cross Talk between Lipid Metabolism and Inflammatory Markers in Patients with Diabetic Retinopathy
- Cholesterol in T cells : homeostasis, plasma membrane organization and signaling
- Therapeutic Implications of Thymoquinone in the Management of Diabetes mellitus and its Complications
- Triglycerides and Coronary Heart Disease: Implications of Recent Clinical Trials
- Atherogenesis and its relationship to coronary risk factors.
- The mechanism underlying the hypocholesterolaemic activity of aqueous celery extract, its butanol and aqueous fractions in genetically hypercholesterolaemic RICO rats.
- Expression of scavenger receptor class B1 in endometrium and endometriosis.
- Low high-density lipoprotein cholesterol disorders and cardiovascular risk: contribution of associated low-density lipoprotein subclass abnormalities
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