Hypermethylated and downregulated MEIS2 are involved in stemness properties and oxaliplatin‐based chemotherapy resistance of colorectal cancer
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Summary
Meis Homeobox 2 (MEIS2) had increased promoter hypermethylation and was downregulated in poor L‐OHP response mCRC tissues, and Gene set enrichment analysis showed that MEIS2 might be involved in the Wnt/β‐catenin pathway.
- Type
- article
- Published
- 2019-10-01
- Cited by
- 34
- References
- 56
- Access
- Open access
- OpenAlex
- https://openalex.org/W30859572
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:75137269
Keywords
sed, Computer science
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Cited by
- Cannabidiol Overcomes Oxaliplatin Resistance by Enhancing NOS3- and SOD2-Induced Autophagy in Human Colorectal Cancer Cells
- MEIS transcription factors in development and disease
- A positive feedback loop of β-catenin/CCR2 axis promotes regorafenib resistance in colorectal cancer
- Epigenetic silencing of MEIS2 in prostate cancer recurrence
- Identification of hub methylated‐CpG sites and associated genes in oral squamous cell carcinoma
- Role of DNA Methylation in the Resistance to Therapy in Solid Tumors
- ZFAS1 Promotes Cisplatin Resistance via Suppressing miR-421 Expression in Oral Squamous Cell Carcinoma
- Hub Genes Identification in a Murine Model of Allergic Rhinitis Based on Bioinformatics Analysis
- Oncogenic and tumor suppressor function of MEIS and associated factors
- Suppression MGP inhibits tumor proliferation and reverses oxaliplatin-resistance in colorectal cancer.
- Reactivation of oncogenes involved in G1/S transcription and apoptosis pathways by low dose decitabine promotes HT29 human colon cancer cell growth in vitro.
- Systematic Investigation of DNA Methylation Associated With Platinum Chemotherapy Resistance Across 13 Cancer Types
- LINC01234 aggravates cell growth and migration of triple‐negative breast cancer by activating the Wnt pathway
- Network analysis with biological data of cancer patients: A scoping review
- Insights into Mechanisms of Tumorigenesis in Neuroendocrine Neoplasms
- Regulation of signal transduction pathways in colorectal cancer: implications for therapeutic resistance
- CPT2 downregulation triggers stemness and oxaliplatin resistance in colorectal cancer via activating the ROS/Wnt/β-catenin-induced glycolytic metabolism.
- MicroRNA-18 facilitates the stemness of gastric cancer by downregulating HMGB3 though targeting Meis2
- HAMP as a Prognostic Biomarker for Colorectal Cancer Based on Tumor Microenvironment Analysis
- Transcription Factor ELF1 Modulates Cisplatin Sensitivity in Prostate Cancer by Targeting MEIS Homeobox 2.
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