Autophagy and its role in gastric cancer.
Explore this paper's citation graph
Summary
Research progress regarding autophagy and its significant role in gastric cancer is described and inhibitors and inducers show promise for GC treatment.
- Type
- review
- Published
- 2019-02-01
- Cited by
- 169
- References
- 124
- OpenAlex
- https://openalex.org/W2900750994
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:53767847
Keywords
Autophagy, PI3K/AKT/mTOR pathway, Cell biology, Biology, AMPK
References
- Autophagy in Vascular Disease
- The role of autophagy in bacterial infections.
- Fluorouracil induces autophagy-related gastric carcinoma cell death through Beclin-1 upregulation by miR-30 suppression
- Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease
- Expressional and mutational analyses of ATG5 gene in prostate cancers
- LC3A‐Positive “Stone‐Like” Structures Predict an Adverse Prognosis of Gastric Cancer
- A Prospective, Phase I/II Study of Everolimus and Temozolomide in Patients with Advanced Pancreatic Neuroendocrine Tumor
- The critical molecular interconnections in regulating apoptosis and autophagy
- Regulation of mTORC1 by PI3K Signaling
- Correlative Analysis of Genetic Alterations and Everolimus Benefit in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: Results From BOLERO-2.
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- Beclin 1 mRNA Strongly Correlates with Bcl-XLmRNA Expression in Human Hepatocellular Carcinoma
- Mammalian autophagy: core molecular machinery and signaling regulation
- Kaempferol induces autophagy through AMPK and AKT signaling molecules and causes G2/M arrest via downregulation of CDK1/cyclin B in SK-HEP-1 human hepatic cancer cells.
- Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma
- Tumor vessel normalization by chloroquine independent of autophagy.
- Two ubiquitin-like conjugation systems that mediate membrane formation during autophagy.
- Autophagy: Renovation of Cells and Tissues
- Vacuolating Cytotoxin and Variants in Atg16L1 that Disrupt Autophagy Promote Helicobacter pylori Infection in Humans
- The expression of beclin-1, an autophagic gene, in hepatocellular carcinoma associated with clinical pathological and prognostic significance
Cited by
- Immunohistochemical Expression of Autophagy-Related Proteins in Advanced Tubular Gastric Adenocarcinomas and Its Implications
- Inhibition of human glioblastoma cell invasion involves PION@E6 mediated autophagy process
- The neuroprotective effects of curcumin are associated with the regulation of the reciprocal function between autophagy and HIF-1α in cerebral ischemia-reperfusion injury
- Modulating autophagy as a therapeutic strategy for the treatment of paediatric high‐grade glioma
- Hypoxia-Induced Autophagy Degrades Stromal Lumican into Tumor Microenvironment of Pancreatic Ductal Adenocarcinoma: A Mini-Review
- A Novel Role for Helicobacter pylori Gamma-Glutamyltranspeptidase in Regulating Autophagy and Bacterial Internalization in Human Gastric Cells
- Adapting and Surviving: Intra and Extra-Cellular Remodeling in Drug-Resistant Gastric Cancer Cells
- Bismuth embedded silica nanoparticles loaded with autophagy suppressant to promote photothermal therapy.
- Downregulation of long noncoding RNA LINC01419 inhibits cell migration, invasion, and tumor growth and promotes autophagy via inactivation of the PI3K/Akt1/mTOR pathway in gastric cancer
- Prognostic Significance of LC3B and p62/SQSTM1 Expression in Gastric Adenocarcinoma
- Grape Seed Proanthocyanidins Induce Autophagy and Modulate Survivin in HepG2 Cells and Inhibit Xenograft Tumor Growth in Vivo
- ERas Enhances Resistance to Cisplatin-Induced Apoptosis by Suppressing Autophagy in Gastric Cancer Cell
- FAS/FAS-L-mediated apoptosis and autophagy of SPC-A-1 cells induced by water-soluble polysaccharide from Polygala tenuifolia.
- Gastric Tumor Microenvironment.
- A Review of Research Progress in Multidrug-Resistance Mechanisms in Gastric Cancer
- Autophagy-deficiency in bone marrow mononuclear cells from patients with myasthenia gravis: a possible mechanism of pathogenesis
- Design, synthesis and anticancer activity of naphthoquinone derivatives
- Effects of autophagy-associated genes on the prognosis for lung adenocarcinoma
- Effect of combination of curcumin and GLUT‐1 AS‐ODN on radiosensitivity of laryngeal carcinoma through regulating autophagy
- Epithelial-mesenchymal transition suppresses ERas to activate autophagy in retinal pigment epithelial cells in proliferative vitreoretinopathy.
Related papers
- The AMPK-dependent inhibition of autophagy plays a crucial role in protecting photoreceptor from photooxidative injury.
- Autophagy is a survival force via suppression of necrotic cell death.
- Autophagy: Executor and Manager of Programmed Cell Death
- Autophagic cell death
- Cell death by autophagy: facts and apparent artefacts
- Autophagy in cell death: an innocent convict?
- The complex roles and regulation of autophagy during cell death
- Autophagic Survival Precedes Programmed Cell Death in Wheat Seedlings Exposed to Drought Stress
- Autophagy in Cancer Cell Death