Using hiCLIP to identify RNA duplexes that interact with a specific RNA-binding protein

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Summary

The use of an adaptor that links the two arms of the RNA duplex permits hiCLIP to unambiguously identify the duplexes, including those that are challenging to predict computationally, such as intermolecular and long-range intramolecular duplexe.

Type
article
Published
2017-02-23
Cited by
29
References
51
Access
Open access

Keywords

Computer science

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