Up-regulation of GTPBP4 in colorectal carcinoma is responsible for tumor metastasis.
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Summary
Research uncovered that GTPBP4 promotes CRC metastasis by disrupting actin cytoskeleton, which is mediated by the reduced RhoA activity, which will be promising for CRC patients with metastases.
- Type
- article
- Published
- 2016-11-04
- Cited by
- 23
- References
- 32
- OpenAlex
- https://openalex.org/W27720713
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5072465
Keywords
Action (physics), Citizen journalism, Sociology, Computer science, World Wide Web
References
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Cited by
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- GTPBP4 Promotes Gastric Cancer Progression via Regulating P53 Activity
- Proteome profiling to identify peroxiredoxin 1 interacting protein partners in nicotine-associated oral leukoplakia.
- Oral Soft Tissue Regeneration Using Nano Controlled System Inducing Sequential Release of Trichloroacetic Acid and Epidermal Growth Factor
- PBX3 Promotes Tumor Growth and Angiogenesis via Activation of AT1R/VEGFR2 Pathway in Papillary Thyroid Carcinoma
- A Normalization Method Utilizing Endogenous Proteins for Quantitative Proteomics.
- Network-based identification of biomarkers for colon adenocarcinoma
- Determining the Clinical Value and Critical Pathway of GTPBP4 in Lung Adenocarcinoma Using a Bioinformatics Strategy: A Study Based on Datasets from The Cancer Genome Atlas
- Integrated bioinformatic analysis of RNA binding proteins in hepatocellular carcinoma
- A translation control module coordinates germline stem cell differentiation with ribosome biogenesis during Drosophila oogenesis
- Upregulation of GTPBP4 Promotes the Proliferation of Liver Cancer Cells
- LncRNA FGD5-AS1 functions as an oncogene to upregulate GTPBP4 expression by sponging miR-873-5p in hepatocellular carcinoma
- Whole exome analysis of patients in Japan with hearing loss reveals high heterogeneity among responsible and novel candidate genes
- The Prognostic Signature and Therapeutic Value of Phagocytic Regulatory Factors in Prostate Adenocarcinoma (PRAD)
- Integrated Analysis of Genomic and Transcriptomic Profiles Identified the Role of GTP Binding Protein-4 (GTPBP4) in Breast Cancer
- Computational Characterizing Necroptosis Reveals Implications for Immune Infiltration and Immunotherapy of Hepatocellular Carcinoma
- GTPBP4: A New Therapeutic Target Gene Promotes Tumor Progression in Non-Small Cell Lung Cancer via EMT
- Transcriptome analysis of the adenoma–carcinoma sequences identifies novel biomarkers associated with development of canine colorectal cancer
- Significance of RNA Processing Factors in Prognosis and Treatment of Hepatocellular Carcinoma: Implications for Precision Medicine
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