Configuration and rearrangement of the human GAGE gene clusters.
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Summary
Analysis of Rothmund -Thomson syndrome kindreds and probands showed GAGE cluster inheritance and stability indistinguishable from that found in non-RTS individuals, which support the concept of evolutionarily rapid rearrangement of clustered repetitive sequences in the human genome.
- Type
- article
- Published
- 2011-05-15
- Cited by
- 11
- References
- 31
- Access
- Open access
- OpenAlex
- https://openalex.org/W26758724
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:8035561
Keywords
Gene, Chromosome, Cluster (spacecraft), Proband, Gene cluster
References
- A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma.
- HUMAN RIBOSOMAL RNA GENE CLUSTERS ARE RECOMBINATIONAL HOTSPOTS IN CANCER
- Characterization of the GAGE genes that are expressed in various human cancers and in normal testis.
- The expression of GAGE gene can predict aggressive biologic behavior of intestinal type of stomach cancer.
- T cell immunomonitoring and tumor responses in patients immunized with a complex of cholesterol-bearing hydrophobized pullulan (CHP) and NY-ESO-1 protein.
- An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members.
- MAGE-1, GAGE-1/-2 gene expression in FNAB of classic variant of papillary thyroid carcinoma and papillary hyperplasia in nodular goiter.
- A Member of the GAGE Family of Tumor Antigens is an Anti-Apoptotic Gene that Confers Resistance to Fas/CD95/APO-1, Interferon-g, Taxol and g-irradiation
- Genome-wide analysis of cancer/testis gene expression
- Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE‐3 and presented by HLA‐A1
- mRNA expression of tumor‐associated antigens in melanoma tissues and cell lines
- Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance
- Vaccination with an NY-ESO-1 peptide of HLA class I/II specificities induces integrated humoral and T cell responses in ovarian cancer
- GAGE, an Antiapoptotic Protein Binds and Modulates the Expression of Nucleophosmin/B23 and Interferon Regulatory Factor 1
- MAGE BAGE and GAGE genes expression in fresh epithelial ovarian carcinomas.
- MAGE, BAGE and GAGE: tumour antigen expression in benign and malignant ovarian tissue.
- Analysis of the largest tandemly repeated DNA families in the human genome
- Prognostic significance of GAGE detection in bone marrows on survival of patients with metastatic neuroblastoma.
- Recent duplication and positive selection of the GAGE gene family
- CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens
Cited by
- GAGE12 mediates human gastric carcinoma growth and metastasis
- Loss of Bloom syndrome protein causes destabilization of genomic architecture and is complemented by ectopic expression of Escherichia coli Recg in human cells
- Oncogenic cancer/testis antigens: prime candidates for immunotherapy
- A novel tRNA variable number tandem repeat at human chromosome 1q23.3 is implicated as a boundary element based on conservation of a CTCF motif in mouse
- GAGE Cancer-Germline Antigens Are Recruited to the Nuclear Envelope by Germ Cell-Less (GCL)
- X chromosomal mutations and spermatogenic failure.
- The unique C- and N-terminal sequences of Metallothionein isoform 3 mediate growth inhibition and Vectorial active transport in MCF-7 cells
- Telomere-to-telomere assembly of a complete human X chromosome
- PCR amplicons identify widespread copy number variation in human centromeric arrays and instability in cancer
- Research progress in enhancing the precision of TCR-T cell therapy targeting cancer-testis antigens for cancer treatment in elderly patients
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