Oncogenic cancer/testis antigens: prime candidates for immunotherapy
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Summary
Evidence is provided that many cancer/testis antigens, in fact, have oncogenic functions, including support of growth, survival and metastasis, which has the potential to deliver more effective cancer vaccines.
- Type
- review
- Published
- 2015-06-30
- Cited by
- 313
- References
- 119
- Access
- Open access
- OpenAlex
- https://openalex.org/W1813394859
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13469428
Keywords
Immunotherapy, Cancer, Medicine, Cancer immunotherapy, Antigen
References
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- Pancreatic cancer vaccine: a unique potential therapy
- Lack of ADAM2, CALR3 and SAGE1 Cancer/Testis Antigen Expression in Lung and Breast Cancer
- EIF2S3Y suppresses the pluripotency state and promotes the proliferation of mouse embryonic stem cells
- Personalized Oncology Meets Immunology: The Path Towards Precision Immunotherapy
- Comment on ‘Tumour antigen expression in hepatocellular carcinoma in a low-endemic western area'
- Lentivirus-mediated knockdown of TSP50 suppresses the growth of non-small cell lung cancer cells via G0/G1 phase arrest.
- Immunotherapy for genitourinary cancer: state of the art and new perspectives
- AKAP4 mediated tumor malignancy in esophageal cancer.
- Differences in somatic mutation landscape of hepatocellular carcinoma in Asian American and European American populations
- LEM domain containing 1 promotes oral squamous cell carcinoma invasion and endothelial transmigration
- Ectopic Expression of Testis Germ Cell Proteins in Cancer and Its Potential Role in Genomic Instability
- Human Leukocyte Antigen (HLA) Peptides Derived from Tumor Antigens Induced by Inhibition of DNA Methylation for Development of Drug-facilitated Immunotherapy *
- Profiling cancer testis antigens in non-small-cell lung cancer.
- The gender perspective in cancer research and therapy: novel insights and on-going hypotheses.
- Current status of engineered T-cell therapy for synovial sarcoma.
- Cigarette smoke extracts induce overexpression of the proto-oncogenic gene interleukin-13 receptor α2 through activation of the PKA-CREB signaling pathway to trigger malignant transformation of lung vascular endothelial cells and angiogenesis.
- Selection of epitopes from self-antigens for eliciting Th2 or Th1 activity in the treatment of autoimmune disease or cancer
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