Delayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental stroke

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Summary

Whether delayed minocycline inhibits brain MMPs activated by ischemia in a model of temporary occlusion in Wistar rats is investigated and it is likely to be selective for MMP-9 at low doses.

Type
article
Published
2006-07-17
Cited by
195
References
38
Access
Open access

Keywords

Minocycline, Neuroprotection, Matrix metalloproteinase, Ischemia, Pharmacology

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