Clock Genes Control Cortical Critical Period Timing

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Summary

It is shown that circadian clock genes control the onset of critical period plasticity in the neocortex of Clock-deficient mice, and unique downstream gene sets controlling synaptic events and cellular homeostasis for proper maturation and maintenance were found to be regulated by CLOCK specifically within PV-cells.

Type
article
Published
2015-03-19
Cited by
105
References
78
Access
Open access

Keywords

Philosophy

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