TIM-1 deficiency eliminates airway hyperreactivity triggered by the recognition of airway cell death
Explore this paper's citation graph
Summary
A novel pathway in which TIM-1, a receptor for phosphatidylserine expressed by apoptotic cells, drives the development of asthma by sensing and responding to injured and apoptotic airway epithelial cells is defined.
- Type
- article
- Published
- 2013-05-11
- Cited by
- 30
- References
- 57
- Access
- Open access
- OpenAlex
- https://openalex.org/W23672783
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:36934959
Keywords
Cobalt, Kinetics, Hydrogen, Chemistry, Deuterium
References
- Respiratory syncytial virus infections in the adult asthmatic – mechanisms of host susceptibility and viral subversion
- Tim1 and Tim3 are not essential for experimental allergic asthma
- Apoptotic Cells Activate NKT Cells through T Cell Ig-Like Mucin-Like–1 Resulting in Airway Hyperreactivity
- Cross sectional retrospective study of prevalence of atopy among Italian military students with antibodies against hepatitis a virus
- Ozone-induced airway inflammation in human subjects as determined by airway lavage and biopsy.
- The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?
- TIM1 haplotype may control the disease progression to AIDS in a HIV-1-infected female cohort in Thailand
- Epithelial cell proliferation contributes to airway remodeling in severe asthma.
- TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.
- Structures of T cell immunoglobulin mucin protein 4 show a metal-Ion-dependent ligand binding site where phosphatidylserine binds.
- Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family
- The Burden of Respiratory Syncytial Virus Infection in Young Children
- Respiratory syncytial virus infection in elderly and high-risk adults.
- Genetic variants of the T-cell immunoglobulin mucin 1 but not the T-cell immunoglobulin mucin 3 gene are associated with asthma in an African American population.
- Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice.
- Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
- Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease.
- The Emerging Role of T Cell Ig Mucin-1 (TIM-1) in The Mechanism of Liver Ischemia and Reperfusion Injury
- The many paths to asthma: phenotype shaped by innate and adaptive immunity
- Asthma phenotypes: the evolution from clinical to molecular approaches
Cited by
- The role of TIM-1 in enveloped virus entry
- Innate immunity in asthma
- Phosphatidylserine receptors: enhancers of enveloped virus entry and infection
- Chemerin suppresses murine allergic asthma by inhibiting CCL2 production and subsequent airway recruitment of inflammatory dendritic cells
- KIM‐1‐/TIM‐1‐mediated phagocytosis links ATG5‐/ULK1‐dependent clearance of apoptotic cells to antigen presentation
- Innate lymphoid cells in asthma: Will they take your breath away?
- Regulation of mast cell function by TIM-1 and TIM-3 signaling
- Immune Regulation and Antitumor Effect of TIM-1
- IL-27 attenuates airway inflammation in a mouse asthma model via the STAT1 and GADD45γ/p38 MAPK pathways
- Associations Between TIM1 Polymorphisms and Dilated Cardiomyopathy in a Han Chinese Population.
- Arenaviruses: mechanisms of antibody-mediated neutralization and an alternative route of entry
- TIM4-TIM1 interaction modulates Th2 pattern inflammation through enhancing SIRT1 expression
- IL-17-producing-ST2+ILC2 plays a pathogenic role in lung inflammation
- The effects of resiquimod in an ovalbumin‐induced allergic rhinitis model
- SEB/OVA Facilitated TIM4 Expression in Intestinal Antigen Presenting Cells via Acetylation of Histone H3
- TIM-1 Mediates Dystroglycan-Independent Entry of Lassa Virus
- Role of CD1d- and MR1-Restricted T Cells in Asthma
- Fine Particulate Matter-Induced Exacerbation of Allergic Asthma via Activation of T-cell Immunoglobulin and Mucin Domain 1
- Preventative tracheal administration of interleukin‐27 attenuates allergic asthma by improving the lung Th1 microenvironment
- TIM-1 Serves as a Nonredundant Receptor for Ebola Virus, Enhancing Viremia and Pathogenesis
Related papers
- Electron Transfer between Atomic Hydrogen and Cobalt(III) Complexes in Aqueous Solution
- Spectroscopic and solution properties of the cobalt(III) hexaimidazole ion
- Chemical effects of electron capture in 57Co(III)(1–10 phenanthroline)3(ClO4)3.2H2O☆☆☆
- Nuclear magnetic resonance study of ligand-exchange kinetics of cobalt(II)- and nickel(II)-dimethyl sulfoxide complexes in mixed solvents
- ChemInform Abstract: CYANIDE EXCHANGE KINETICS FOR PLANAR TETRACYANOMETALATE COMPLEXES BY CARBON‐13 NMR
- Ligand-exchange reactions in the analysis of cobalt complexes by atomic-absorption spectrophotometry
- STRUCTURAL CHARACTERIZATION OF BI-NUCLEAR COBALT(III) AXIAL-METHYL ALCOHOL-HYDROCHLORIC ACID TETRAPHENYL-PORPHYRIN COMPLEX
- ChemInform Abstract: TETRAGLYCINE COMPLEXES OF COBALT(III): PREPARATIONS, PROTON AND CARBON‐13 NMR SPECTRA, ABSORPTION SPECTRA, AND REACTIONS IN ACID
- Synthesis, characterization, and proton magnetic resonance spectra of nickel(II) and cobalt(II) complexes with o-mercaptobenzaldiminates
- Synthesis and Some Properties of Transition Metal Complexes with Octa(sulfophenyl)tetrapyrazinoporphyrazine