Asthma phenotypes: the evolution from clinical to molecular approaches
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Summary
Ongoing studies of large-scale, molecularly and genetically focused and extensively clinically characterized cohorts of asthma should enhance the ability to molecularly understand these phenotypes and lead to more targeted and personalized approaches to asthma therapy.
- Type
- review
- Published
- 2012-05-01
- Cited by
- 2,336
- References
- 145
- OpenAlex
- https://openalex.org/W2013105339
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:205389006
Keywords
Phenotype, Asthma, Genetic heterogeneity, Clinical phenotype, Precision medicine
References
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- Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma
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Cited by
- Asthma and Obstructive Sleep Apnea
- Gene-environment interactions in asthma and allergic diseases: challenges and perspectives.
- TIM-1 deficiency eliminates airway hyperreactivity triggered by the recognition of airway cell death
- Marked epithelial cell pathology and leukocyte paucity in persistently symptomatic severe asthma.
- Reproducibility of the bronchoconstrictive response to eucapnic voluntary hyperpnoea.
- Role of the Histamine H4-Receptor in Bronchial Asthma.
- Consistency of T2 Gene Signatures in Severe Asthma. Key to Effective Treatments or Merely the Tip of the Iceberg?
- Severe asthma in humans and mouse model suggests a CXCL10 signature underlies corticosteroid-resistant Th1 bias.
- Acute Respiratory Distress Syndrome
- Adipokines in inflammatory lung diseases
- Cytokine-induced killer cells: A novel treatment for allergic airway inflammation
- miR-142-3p is associated with aberrant WNT signaling during airway remodeling in asthma.
- A novel microRNA miR-1165-3p as a potential diagnostic biomarker for allergic asthma
- Equine asthma: Integrative biologic relevance of a recently proposed nomenclature
- Innate lymphoid cells in asthma: pathophysiological insights from murine models to human asthma phenotypes
- Basic characteristics and clinical value of FeNO in smoking asthmatics—a systematic review
- Asthma bronchiale im Kindesalter
- Dupilumab in persistent asthma.
- Introduction to asthma and phenotyping.
- Die DREAM-Studie – Abschluss einer Selbstfindung und Beginn einer Zeitenwende
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