Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation
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Summary
It is concluded that E-cadherin-based FAJs connect forming cell–cell adhesions to the contractile actomyosin cytoskeleton and are sites of Cadherin mechanosensing, which is a driving force in epithelial barrier formation.
- Type
- article
- Published
- 2012-09-11
- Cited by
- 117
- References
- 69
- OpenAlex
- https://openalex.org/W23213393
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1995743
Keywords
Political science
References
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- α-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junction
- Vinculin Is a Dually Regulated Actin Filament Barbed End-capping and Side-binding Protein
- Mechanotransduction across the cell surface and through the cytoskeleton.
- Actomyosin tension is required for correct recruitment of adherens junction components and zonula occludens formation.
- The mechanical integrin cycle
- α-Catenin Is a Molecular Switch that Binds E-Cadherin-β-Catenin and Regulates Actin-Filament Assembly
Cited by
- Structural and functional characterization of Caenorhabditis elegans α-catenin reveals constitutive binding to β-catenin and F-actin
- Integration of cell-cell adhesion and contractile actomyosin activity during morphogenesis.
- Cell Adhesion in Epidermal Development and Barrier Formation
- Mechanosensitive Adaptation of E-Cadherin Turnover across adherens Junctions
- Structural Determinants of the Mechanical Stability of α-Catenin*
- α-Catenin–mediated cadherin clustering couples cadherin and actin dynamics
- Synaptopodin couples epithelial contractility to α-actinin-4–dependent junction maturation
- Dynamic visualization of α-catenin reveals rapid, reversible conformation switching between tension states
- Myosin 1e is a component of the glomerular slit diaphragm complex that regulates actin reorganization during cell-cell contact formation in podocytes.
- HGF signaling regulates Claudin-3 dynamics through its C-terminal tyrosine residues
- The minimal cadherin-catenin complex binds to actin filaments under force
- &agr;-Catenin cytomechanics – role in cadherin-dependent adhesion and mechanotransduction
- Mechanical control of the endothelial barrier
- Vinculin and metavinculin: Oligomerization and interactions with F‐actin
- Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling
- Substrate Stiffness Mediated Metastasis Like Phenotype of Colon Cancer Cells is Independent of Cell to Gel Adhesion
- Effects of capsicum oleoresin, garlic botanical, and turmeric oleoresin on gene expression profile of ileal mucosa in weaned pigs.
- A multicellular view of cytokinesis in epithelial tissue.
- Cadherin mechanotransduction in tissue remodeling
- Adherens junction treadmilling during collective migration
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