Synergystic induction of HIF-1α transcriptional activity by hypoxia and lipopolysaccharide in macrophages

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Summary

The results demonstrate that LPS and hypoxia act synergistically to induce HIF-1α-transcriptional activity and they emphasize the existence of a cross talk between hypoxic and non-hypoxic signaling pathways in the regulation of macrophages gene expression.

Type
article
Published
2008-01-15
Cited by
69
References
63
Access
Open access

Keywords

Geology

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