Maternal diet, aging and diabetes meet at a chromatin loop
Explore this paper's citation graph
Summary
Novel findings in the context of the growing list of epigenetic mechanisms by which the environment can affect gene activity are discussed and their implications for the understanding of the mechanistic basis of the development of type 2 diabetes with age are emphasized.
- Type
- article
- Published
- 2011-05-01
- Cited by
- 27
- References
- 34
- Access
- Open access
- OpenAlex
- https://openalex.org/W18049820
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9606283
Keywords
Epigenetics, Chromatin, Biology, Enhancer, Transcription factor
References
- Epigenetic regulation of aging.
- Does early growth affect long-term risk factors for cardiovascular disease?
- Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
- Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes.
- Breast-feeding and childhood obesity—a systematic review
- Poor maternal nutrition followed by accelerated postnatal growth leads to telomere shortening and increased markers of cell senescence in rat islets
- Fetal and infant growth and impaired glucose tolerance at age 64.
- Lifespan: Catch-up growth and obesity in male mice
- An evaluation of 3C-based methods to capture DNA interactions
- Low birth weight is associated with NIDDM in discordant monozygotic and dizygotic twin pairs
- Early growth determines longevity in male rats and may be related to telomere shortening in the kidney
- Dynamic DNA methylation programs persistent adverse effects of early-life stress
- Maternal diet and aging alter the epigenetic control of a promoter–enhancer interaction at the Hnf4a gene in rat pancreatic islets
- Child health, developmental plasticity, and epigenetic programming.
- Mechanisms of Disease: the developmental origins of disease and the role of the epigenotype
- Relation between weight gain and beta-cell secretory activity and non-esterified fatty acid production in 7-year-old African children: results from the Birth to Ten study
- Nutrition in infancy and long-term risk of obesity: evidence from 2 randomized controlled trials.
- Effect of In Utero and Early-Life Conditions on Adult Health and Disease
- Histone Modifications at Human Enhancers Reflect Global Cell Type-Specific Gene Expression
- Size at birth as a predictor of mortality in adulthood: a follow-up of 350 000 person-years.
Cited by
- Influence of maternal macronutritional diet on the developme(n)t of obesity, glycometabolic disorders, and anxiety-/depression- like behaviour of offspring
- Inhibition of DNA methyltransferase 1 increases nuclear receptor subfamily 4 group A member 1 expression and decreases blood glucose in type 2 diabetes
- Obesity and Endocrine Dysfunction Programmed by Maternal Smoking in Pregnancy and Lactation
- Epigenetic mechanisms linking early nutrition to long term health.
- Diabetes mellitus associada à desnutrição proteica: realidade ou ficção?
- Developmental and environmental epigenetic programming of the endocrine pancreas: consequences for type 2 diabetes
- Epigenetics and Obesity: A Relationship Waiting to Be Explained
- Maternal low-protein diet alters the expression of real-time quantitative polymerase chain reaction reference genes in an age-, sex-, and organ-dependent manner in rat offspring.
- A model for the 3D chromatin architecture of pro and eukaryotes.
- Mitotic chromosome structure.
- Early-life nutritional programming of longevity
- PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes
- Regulation of Liver Development: Implications for Liver Biology across the Lifespan
- Le nouveau paradigme de l’origine développementale de la santé et des maladies (DOHaD) - Épigénétique, environnement : preuves et chaînons manquants
- The role of diet and exercise in the transgenerational epigenetic landscape of T2DM
- Maternal Exposure to Bisphenol-A During Pregnancy Increases Pancreatic β-Cell Growth During Early Life in Male Mice Offspring.
- Parental High-Fat Diet Promotes Inflammatory and Senescence-Related Changes in Prostate
- Nutriepigenomics and malnutrition.
- Early gestational maternal low-protein diet diminishes hepatic response to fasting in young adult male mice
- Combination and haplotype effects of protein tyrosine phosphatase receptor type D gene polymorphisms on type 2 diabetes in a sample of Iranian population: A pilot study
Related papers
- Recruitment of Transcription Complexes to Enhancers and the Role of Enhancer Transcription
- Promoter targeting sequence mediates enhancer interference in the Drosophila embryo
- Increased Enhancer—Promoter Interactions during Developmental Enhancer Activation in Mammals
- Increased Enhancer-Promoter Interactions during Developmental Enhancer Activation in Mammals
- Dissection of thousands of cell type-specific enhancers identifies dinucleotide repeat motifs as general enhancer features
- Developmental and housekeeping transcriptional programs display distinct modes of enhancer-enhancer cooperativity in Drosophila
- Enhancer cooperativity can compensate for loss of activity over large genomic distances
- Enhancer, epigenetics, and human disease.
- Plant chromatin, metabolism and development - an intricate crosstalk.
- Single-molecule imaging of epigenetic complexes in living cells: insights from studies on Polycomb group proteins