Expression of Beclin Family Proteins Is Associated with Tumor Progression in Oral Cancer
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Summary
Findings suggest Beclin proteins are associated with tumorigenesis, similar to other autophagy-related proteins that show similar amino acid sequences and domain structures in cancer progression.
- Type
- article
- Published
- 2015-10-27
- Cited by
- 24
- References
- 54
- Access
- Open access
- OpenAlex
- https://openalex.org/W26506105
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18509343
Keywords
Veterinary medicine, Value (mathematics), Animal welfare, Medicine, Business
References
- G-protein-coupled receptors and cancer
- Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function.
- Induction of autophagy and inhibition of tumorigenesis by beclin 1
- High Beclin 1 expression defines a poor prognosis in endometrial adenocarcinomas.
- Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy.
- Prognostic significance of p62/SQSTM1 subcellular localization and LC3B in oral squamous cell carcinoma
- The American Joint Committee on Cancer: the 7th Edition of the AJCC Cancer Staging Manual and the Future of TNM
- Molecular pathogenesis of head and neck squamous cell carcinoma
- Cellular and metabolic functions for autophagy in cancer cells
- Interaction between Her2 and Beclin-1 Proteins Underlies a New Mechanism of Reciprocal Regulation*
- Beclin 1 expression predicts favorable clinical outcome in patients with diffuse large B-cell lymphoma treated with R-CHOP.
- Decreased Expression of Beclin 1 Correlates Closely with Bcl-xL Expression and Poor Prognosis of Ovarian Carcinoma
- The significance of expression of autophagy-related gene Beclin, Bcl-2, and Bax in breast cancer tissues
- Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L)
- Global epidemiology of oral and oropharyngeal cancer.
- Autophagy-Mediated Tumor Promotion
- Prognostic Significance of Beclin-1 Expression in Laryngeal Squamous Cell Carcinoma
- Clinicopathologic correlation of beclin-1 expression in pancreatic ductal adenocarcinoma.
- Beclin 1 expression is an independent prognostic factor for gastric carcinomas
- Elevated Beclin 1 expression is correlated with HIF-1α in predicting poor prognosis of nasopharyngeal carcinoma
Cited by
- Upregulation of p72 enhances malignant migration and invasion of glioma cells by repressing Beclin1 expression
- The interplay between autophagy and tumorigenesis: exploiting autophagy as a means of anticancer therapy
- Clathrin‐mediated endocytosis is required for ANE 30‐100K‐induced autophagy
- Monitoring Autophagy Immunohistochemically and Ultrastructurally during Human Head and Neck Carcinogenesis. Relationship with the DNA Damage Response Pathway
- Prognostic and clinicopathological significance of Beclin-1 in non-small-cell lung cancer: a meta-analysis
- Genes involved in the regulation of different types of autophagy and their participation in cancer pathogenesis
- Novel Prognostic and Predictive Markers for Canine Mast Cell Tumours
- MicroRNA-504 functions as a tumor suppressor in oral squamous cell carcinoma through inhibiting cell proliferation, migration and invasion by targeting CDK6.
- The Role of Beclin 1-Dependent Autophagy in Cancer
- shRNA Glut-1 inhibits cell viability, apoptosis and migration of laryngeal carcinoma HEp-2 cells through regulating Beclin-1-mediated autophagy
- Silence of Beclin1 in oral squamous cell carcinoma cells promotes proliferation, inhibits apoptosis, and enhances chemosensitivity.
- Exosome-mediated delivery of miR-30a sensitize cisplatin-resistant variant of oral squamous carcinoma cells via modulating Beclin1 and Bcl2
- Autophagy-Related Beclin 1 and Head and Neck Cancers
- Beclin-1 is a novel predictive biomarker for canine cutaneous and subcutaneous mast cell tumors
- Prognostic value of Beclin 1, EGFR and ALK in non-squamous non-small cell lung cancer
- Transcription of Autophagy Associated Gene Expression as Possible Predictors of a Colorectal Cancer Prognosis
- Autophagy and nuclear morphometry are associated with histopathologic features in esophageal squamous cell carcinoma
- Sesamin-mediated high expression of BECN2 ameliorates cartilage endplate degeneration by reducing autophagy and inflammation
- The role of autophagy dysregulation in low and high-grade nonmuscle invasive bladder cancer: A survival analysis and clinicopathological association.
- Recent development of nanomaterials-based PDT to improve immunogenic cell death
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