Early viral kinetics and treatment outcome in combination of high‐dose interferon induction vs. pegylated interferon plus ribavirin for naïve patients infected with hepatitis C virus of genotype 1b and high viral load
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Summary
The results suggest that early monitoring of viral kinetics is a useful measure to predict virological response, and might facilitate development of rational and effective therapeutic strategies.
- Type
- book
- Published
- 2005-01-01
- Cited by
- 55
- References
- 40
- Access
- Open access
- OpenAlex
- https://openalex.org/W15543591
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24231710
Keywords
Developing country, Principal (computer security), World War II, Political science, Development economics
References
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- Hepatitis C virus-specific T-cell reactivity during interferon and ribavirin treatment in chronic hepatitis C.
- Standardization of Hepatitis C Virus RNA Quantification
- Impact of interferon alfa‐2b and ribavirin on progression of liver fibrosis in patients with chronic hepatitis C
- Monitoring of viral levels during therapy of hepatitis C
- Broad-Spectrum Antiviral Activity of Virazole: 1-f8- D-Ribofuranosyl- 1,2,4-triazole- 3-carboxamide
- Viral kinetics in patients with chronic hepatitis C treated with standard or peginterferon alpha2a.
- Significance of serum hepatitis C virus RNA levels in chronic hepatitis C.
- Effect of interferon therapy on hepatocellular carcinogenesis in patients with chronic hepatitis type C: A long‐term observation study of 1,643 patients using statistical bias correction with proportional hazard analysis
- Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region.
- Molecular mechanisms of action of ribavirin.
- Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy.
- Quantification of the initial decline of serum hepatitis c virus RNA and response to interferon alfa
- Effect of ribavirin on hepatitis C viral kinetics in patients treated with pegylated interferon
- Estimation of early hepatitis C viral clearance in patients receiving daily interferon and ribavirin therapy using a mathematical model
- Viral kinetics in genotype 1 chronic hepatitis C patients during therapy with 2 different doses of peginterferon alfa‐2b plus ribavirin
- Viral Kinetics and Treatment Response in Patients with Hepatitis C During Induction and Standard Interferon Therapy in Combination with Ribavirin
- Factors predictive of response to interferon‐α therapy in hepatitis C virus infection
Cited by
- Treatment of hepatitis C virus genotype 4 with peginterferon alfa-2a: impact of bilharziasis and fibrosis stage.
- Genotype 1b・高ウイルス量のC型慢性肝炎に対する response-guided therapy の検討
- Peginterferon plus ribavirin versus interferon plus ribavirin for chronic hepatitis C.
- Establishment of a Practical Workflow Using a Next Generation Sequencer to Search for Novel SNPs Associated with the Anti-HCV Treatment Response
- Sustained virological responses following standard anti‐viral therapy in decompensated HCV‐infected cirrhotic patients
- Hepatitis C virus: genotype identification and interactions between viral proteases
- Pegylated interferons for chronic hepatitis C virus infection: an indirect analysis of randomized trials
- Prospective study on early virologic response to treatment with interferon alpha-2b plus ribavirin in patients with chronic hepatitis C genotype 1b.
- IP‐10 predicts viral response and therapeutic outcome in difficult‐to‐treat patients with HCV genotype 1 infection
- Amino Acid Substitution in HCV Core Region and Genetic Variation near the IL28B Gene Affect Viral Dynamics during Telaprevir, Peginterferon and Ribavirin Treatment
- Evaluation of long‐term biochemical responses to combination therapy of interferon plus ribavirin in those infected with hepatitis C virus genotype 1b and high baseline viral load
- Identifying HCV genotype 1 patients at risk of relapse
- Pegylated Interferon Alpha‐2b for Patients with HCV Recurrence and Graft Fibrosis Following Liver Transplantation
- Amino Acid Substitutions in the Hepatitis C Virus Core Region and Lipid Metabolism Are Associated with Hepatocarcinogenesis in Nonresponders to Interferon plus Ribavirin Combination Therapy
- Predictors of sustained virological response to a 48-week course of pegylated interferon alfa-2a and ribavirin in patients infected with hepatitis C virus genotype 4
- [Treatment options for chronic hepatitis C virus infection].
- Triple therapy of initial high‐dose interferon with ribavirin and amantadine for patients with chronic hepatitis C
- Interferon (IFN)-gamma-inducible protein-10: association with histological results, viral kinetics, and outcome during treatment with pegylated IFN-alpha 2a and ribavirin for chronic hepatitis C virus infection.
- Prediction of Response to Pegylated Interferon and Ribavirin in Hepatitis C by Polymorphisms in the Viral Core Protein and Very Early Dynamics of Viremia
- Sustained Virologic Response to Peginterferon α-2a and Ribavirin in 335 Patients with Chronic Hepatitis C: A Tertiary Care Center Experience
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