The p53-inducible gene EI24/PIG8 localizes to human chromosome 11q23 and the proximal region of mouse chromosome 9
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Summary
The genomic locus of EI24 was mapped to the proximal region of mouse chromosome 9 and human chromosome 11q23→q24, a region frequently altered in human cancers, and results suggest that EI 24 may play an important role in the p53 tumor suppressor pathway.
- Type
- article
- Published
- 2000-08-07
- Cited by
- 20
- References
- 11
- OpenAlex
- https://openalex.org/W10965130
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20889902
Keywords
Consolidation (business), Materials science, Compressibility, Scanning electron microscope, Composite material
References
- Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization.
- Identification and cloning of EI24, a gene induced by p53 in etoposide-treated cells.
- A model for p53-induced apoptosis
- The Mouse APLP2 Gene
- ei24, a p53 Response Gene Involved in Growth Suppression and Apoptosis
- Development and applications of a molecular genetic linkage map of the mouse genome.
- Tumor surveillance via the ARF-p53 pathway.
- The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2
- Mdm‐2: “big brother” of p53
- ON THE GENERALIZED STRESS-STRAIN BEHAVIOUR OF WET CLAY
- The structure of clay and its importance in foundation engineering
- Theory of Consolidation for Clays
- p53, the Cellular Gatekeeper Review for Growth and Division
Cited by
- The Novel Gene tank, a Tumor Suppressor Homolog, Regulates Ethanol Sensitivity in Drosophila
- Zinc Binding and Redox Control of p53 Structure and Function
- Experimental glaucoma and optic nerve transection induce simultaneous upregulation of proapoptotic and prosurvival genes.
- Ei24-deficiency attenuates protein kinase Cα signaling and skin carcinogenesis in mice.
- Candidate tumour suppressor genes at 11q23–q24 in breast cancer: evidence of alterations in PIG8, a gene involved in p53-induced apoptosis
- Loss of putative tumor suppressor EI24/PIG8 confers resistance to etoposide
- Inactivation of CHEK1 and EI24 is associated with the development of invasive cervical carcinoma: Clinical and prognostic implications
- Apoptosis factor EI24/PIG8 is a novel endoplasmic reticulum-localized Bcl-2-binding protein which is associated with suppression of breast cancer invasiveness.
- miR‐483‐3p plays an oncogenic role in esophageal squamous cell carcinoma by targeting tumor suppressor EI24
- Untersuchungen zur Chemo- und Radiosensitivität und deren Auswirkungen auf Zellzyklus, Apoptoseinduktion und Genexpression in neuroendokrinen Pankreastumorzellen
- Genetic And Neural Mechanisms Underlying Ethanol-Related Behaviors In Drosophila melanogaster
- Integrated analysis of the prognostic value of TP53 dependent etoposide-induced gene 24 in non-small cell lung cancer.
- EI24 Inhibits Cell Proliferation and Drug Resistance of Esophageal Squamous Cell Carcinoma
- Pan-cancer analysis of differential DNA methylation patterns
- Molecular portrait of squamous cell carcinoma of the bovine horn evaluated by high-throughput targeted exome sequencing: a preliminary report
- Prognostic role and immune infiltration characteristics of EI24 in multiple cancer types
- Biological significance, molecular mechanisms and clinical potential of EI24 in cancer
- Microbiota-induced EI24 improves homeostasis but impedes function of alveolar macrophages via metabolic regulation
- InvasivenessAssociated with Suppression of Breast Cancer Binding Protein which Is − Localized Bcl-2 − Reticulum Apoptosis Factor EI 24 / PIG 8 Is a Novel Endoplasmic
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