Activation of Caspase-2 in Apoptosis*

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Summary

It is suggested that the first cleavage of caspase-2 is accomplished by a caspases-3-like activity, and other ICE-like proteases less sensitive to DEVD-CHO may be responsible for activation of cspase-3 and loss of mitochondrial function.

Type
article
Published
1997-08-22
Cited by
190
References
55
Access
Open access

Keywords

Computer science

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