Inhibition of CPP32-like proteases prevents granzyme B- and Fas-, but not granzyme A-based cytotoxicity exerted by CTL clones.

Keywords

Granzyme, Perforin, Granzyme B, CTL*, Proteases

References

• Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site.T Weiss, Matthias Grell, Behnam Hessabi — 1997

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• Cleavage of FLICE (caspase‐8) by granzyme B during cytotoxic T lymphocyte‐induced apoptosisJan Paul Medema, René E. M. Toes, Carsten Scaffidi — 1997
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• Zinc-mediated regulation of caspases activity: dose-dependent inhibition or activation of caspase-3 in the human Burkitt lymphoma B cells (Ramos)Nicolas Schrantz, M-T Auffredou, Marie‐Françoise Bourgeade — 2001
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