Localisation of the multidrug resistance-associated protein, MRP, in resistant large-cell lung tumour cells.
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Summary
Experiments confirmed that MRP is present at the cell surface of these MDR lung tumour cells that overexpress MRP, and MRP was found predominantly in the lighter membrane fractions containing plasma membrane enzyme activity.
- Type
- dissertation
- Published
- 1995-11-09
- Cited by
- 18
- References
- 17
- Access
- Open access
- OpenAlex
- https://openalex.org/W7503777
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3183376
Keywords
Humanities, Physics, Philosophy
References
- The Lec4A CHO glycosylation mutant arises from miscompartmentalization of a Golgi glycosyltransferase
- Mechanisms of multidrug resistance in HL60 cells: detection of resistance-associated proteins with antibodies against synthetic peptides that correspond to the deduced sequence of P-glycoprotein.
- Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.
- The MRP gene associated with a non-P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein.
- P‐glycoprotein: multidrug‐resistance and a superfamily of membrane‐associated transport proteins
- Preparation and properties of plasma membrane and endoplasmic reticulum fragments from isolated rat fat cells.
- Phosphoramidates. V. Probable identity of rat liver microsomal glucose 6-phosphatase, phosphoramidase, and phosphoramidate-hexose phosphotransferase.
- Sequestration of doxorubicin in vesicles in a multidrug-resistant cell line (LZ-100).
- Examination by laser scanning confocal fluorescence imaging microscopy of the subcellular localisation of anthracyclines in parent and multidrug resistant cell lines.
- Regulation by glutathione of drug transport in multidrug-resistant human lung tumour cell lines overexpressing multidrug resistance-associated protein.
- A 190-kilodalton protein overexpressed in non-P-glycoprotein-containing multidrug-resistant cells and its relationship to the MRP gene.
- Immunochemical detection of the multidrug resistance-associated protein MRP in human multidrug-resistant tumor cells by monoclonal antibodies.
- Chemosensitisation and drug accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell lung cancer cells expressing a 190k membrane protein distinct from P-glycoprotein.
- ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein.
- Detection of the M(r) 190,000 multidrug resistance protein, MRP, with monoclonal antibodies.
- Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line.
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- Resistance mechanisms associated with altered intracellular distribution of anticancer agents.
- Investigation of multidrug resistance and invasion in human cancer cell lines
- Mutagenesis of the putative nucleotide-binding domains of the multidrug resistance associated protein (MRP). Analysis of the effect of these mutations on MRP mediated drug resistance and transport
- The Multidrug Resistance Protein 1: A Functionally Important Activation Marker for Murine Th1 Cells1
- Effect of P-glycoprotein and multidrug resistance associated protein gene expression on Tc-99m MIBI imaging in hepatocellular carcinoma.
- Biology of the multidrug resistance-associated protein, MRP.
- Hypotonicity-induced anion fluxes in cells expressing the multidrug-resistance-associated protein, MRP
- Ultrasonic Nanotherapy of Pancreatic Cancer: Lessons from Ultrasound Imaging
- Multidrug resistance mediated by the multidrug resistance protein (MRP) gene.
- Multidrug resistance protein 1-mediated transport of saquinavir by microglia
- Multidrug resistance-associated protein: a protein distinct from P-glycoprotein involved in cytotoxic drug expulsion.
- Transport of glutathione conjugates into secretory vesicles is mediated by the multidrug‐resistance protein 1
- The blood-brain barrier in neuroinflammatory diseases.
- Efficacy of MGI 114 (HMAF) against the MRP+ metastatic MV522 lung carcinoma xenograft
- Induction of autophagy, apoptosis and aquisition of resistance in response to piceatannol toxicity in MOLT-4 human leukemia cells.
- Patho)physiological function of the Multidrug Resistance protein MRP1
- Murine Th 1 Cells Functionally Important Activation Marker The Multidrug Resistance Protein 1 :
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