Calcium channel blockers correct acidosis in ischemic rat brain without altering cerebral blood flow.
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Summary
It is suggested that calcium channel blockers correct ischemic cerebral acidosis by metabolic mechanisms rather than by changes in blood flow, and local cerebral pH in verapamil- or nimodipine-treated rats was significantly different from that in untreated rats.
- Type
- article
- Published
- 1988-10-01
- Cited by
- 42
- References
- 34
- OpenAlex
- https://openalex.org/W3051532
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21231999
Keywords
Political science
References
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- Inhibition by Verapamil of Ischemic Ca2+ Uptake in the Rabbit Hippocampus
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Cited by
- Spinal cord protection with intravenous nimodipine. A functional and morphologic evaluation.
- Glutamate receptor antagonists in experimental focal cerebral ischaemia.
- The Effect of Nimodipine on the Evolution of Human Cerebral Infarction Studied by PET
- The effects of dizocilpine (MK-801), phencyclidine, and nimodipine on infarct size 48 h after middle cerebral artery occlusion in the rat.
- Protective Effect of Nimodipine against Ischemic Neuronal Damage in Rat Hippocampus without Changing Postischemic Cerebral Blood Flow
- A trial of the effect of nimodipine on outcome after head injury
- Effects of a calcium antagonist, lacidipine, on experimental focal cerebral ischemia in rats.
- Disturbances of Calcium Homeostasis in Ischaemic Stroke
- Mechanisms of cerebral vasospasm in subarachnoid haemorrhage.
- Effect of Nimodipine on Regional Cerebral Glucose Metabolism in Patients with Acute Ischemic Stroke as Measured by Positron Emission Tomography
- Effects of dextromethorphan on rat brain during ischemia and reperfusion assessed by magnetic resonance spectroscopy.
- Nimodipine has no effect on the cerebral circulation in conscious pigs, despite an increase in cardiac output
- Hemodynamic and hepatic pH responses to sodium bicarbonate and carbicarb during systemic acidosis
- Nuclear magnetic resonance measurements of intracellular pH: Biomedical implications
- Synergistic internal carotid vasodilator effects of human α‐calcitonin gene‐related peptide and nimodipine in conscious rats
- Nimodipine posttreatment does not increase blood flow in rats with focal cortical ischemia.
- Prostacyclin attenuates in the rabbit hippocampus early consequences of transient complete cerebral ischemia
- Continuous Nimodipine Treatment Attenuates Cortical Infarction in Rats Subjected to 24 Hours of Focal Cerebral Ischemia
- Nimodipine Pretreatment Improves Cerebral Blood Flow and Reduces Brain Edema in Conscious Rats Subjected to Focal Cerebral Ischemia
- Temporal thresholds for neocortical infarction in rats subjected to reversible focal cerebral ischemia.
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