Cerebral Acidosis in Focal Ischemia: I. A Method for the Simultaneous Measurement of Local Cerebral pH with Cerebral Glucose Utilization or Cerebral Blood Flow in the Rat
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Summary
A double-label technique for the simultaneous autoradiographic determination of local cerebral pH (LCpH) using [14C]dimethyloxazolidinedione ([14C)DMO) with either local cerebral glucose utilization (LCGU) or local CBF (LCBF) using either [ 14C]iodoantipyrine ([14 C]IAP).
- Type
- article
- Published
- 1986-12-01
- Cited by
- 15
- References
- 53
- Access
- Open access
- OpenAlex
- https://openalex.org/W2033644670
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:45923253
Keywords
Cerebral blood flow, Chemistry, Middle cerebral artery, Deoxyglucose, Acidosis
References
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- In vivo measurement of regional brain tissue pH using positron emission tomography
- Extracellular pH, Potassium, and Calcium Activities in Progressive Ischaemia of Rat Cortex
- Simultaneous Measurement of Local Glucose Utilization and Blood Flow in the Rat Brain: An Autoradiographic Method Using Two Tracers Labeled with Carbon-14
- Effect of Ischemia on Quantification of Local Cerebral Glucose Metabolic Rate in Man
- Excessive cellular acidosis: an important mechanism of neuronal damage in the brain?
- Evaluation of a Double-Tracer Autoradiographic Technique for the Measurement of Both Local Cerebral Glucose Metabolism and Local Cerebral Blood Flow
- Intracellular pH in the Brain following Transient Ischemia
- Focal Cerebral Ischaemia in the Rat: 2. Regional Cerebral Blood Flow Determined by [14C]Iodoantipyrine Autoradiography following Middle Cerebral Artery Occlusion
- In vivo Measurement of Regional Brain and Tumor pH Using [14C]Dimethyloxazolidinedione and Quantitative Autoradiography
- The induction and reversibility of cerebral acidosis in thiamine deficiency
- Focal Cerebral Ischaemia in the Rat: 1. Description of Technique and Early Neuropathological Consequences following Middle Cerebral Artery Occlusion
- Cerebral Acidosis in Focal Ischemia: II. Nimodipine and Verapamil Normalize Cerebral pH following Middle Cerebral Artery Occlusion in the Rat
- Brain Lactic Acidosis and Ischemic Cell Damage: 1. Biochemistry and Neurophysiology
Cited by
- Calcium channel blockers correct acidosis in ischemic rat brain without altering cerebral blood flow.
- In Vivo Uptake of [3H]Nimodipine in Focal Cerebral Ischemia: Modulation by Hyperglycemia
- Autoradiographic and biochemical imaging in cerebral ischemia.
- Effect of Nimodipine on the Regional Cerebral Acidosis Accompanying Thiamine Deficiency in the Rat
- Simultaneous Determination of Regional Cerebral Blood Flow, Glucose Metabolism, and pH in Acute Experimental Allergic Encephalomyelitis
- Cerebral Acidosis in Focal Ischemia: II. Nimodipine and Verapamil Normalize Cerebral pH following Middle Cerebral Artery Occlusion in the Rat
- The Effects of a Competitive NMDA Receptor Antagonist (CGS-19755) on Cerebral Blood Flow and pH in Focal Ischemia
- Nimodipine Prevents Hyperglycemia-Induced Cerebral Acidosis in Middle Cerebral Artery Occluded Rats
- In vivo measurement of superoxide in the cerebral cortex during anoxia-reoxygenation and ischemia-reperfusion.
- Quantitative Multiple Tracer Autoradiography: Considerations in Optimizing Precision and Accuracy
- Fluorometric measurement of intracellular pH in vivo in feline cerebral cortex during ischemia and reperfusion.
- Optical Imaging of Brain Function and Metabolism
- 5 – Histopathology of Cerebral Ischemia
- Chapter 41 – Histopathology of Cerebral Ischemia
- Model Fitting with Spatial Constraint for Parametric Imaging in Dynamic PET Studies
- [4] - Double- and Single-Label Quantitative Autoradiography for Cerebral Physiology
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