Tissue localization of 11β-hydroxysteroid dehydrogenase and its relationship to the glucocorticoid receptor
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Summary
The possibility of multiple dehydrogenase species in mineralocorticoid target tissues is consistent with the hypothesis that the ubiquitous ‘native’ 1.4 kB hepatic enzyme regulates the GR, and these separate dehydrogenases regulate the MR.
- Type
- article
- Published
- 1992-01-01
- Cited by
- 119
- References
- 42
- OpenAlex
- https://openalex.org/W1734933
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:38908895
Keywords
Computer science
References
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- Localization of renal 11 beta-dehydrogenase by in situ hybridization: autocrine not paracrine protector of the mineralocorticoid receptor.
- A role for corticosteroid-binding globulin in delivery of cortisol to activated neutrophils.
- Regulation of active sodium and potassium transport in the distal colon of the rat. Role of the aldosterone and glucocorticoid receptors.
Cited by
- Genetic diseases of steroid metabolism.
- Obesity, 11β-hydroxysteroid dehydrogenase and metabolic changes in the pathogenesis of idiopathic intracranial hypertension
- Non-genomic effects of glucocorticoids in the neural system. Evidence, mechanisms and implications.
- Carbonyl reduction by 3 alpha-HSD from Comamonas testosteroni--new properties and its relationship to the SCAD family.
- The Establishment of Spermatogenesis in the Seminiferous Epithelium of the Pubertal Golden Hamster (Mesocricetus auratus)
- Fetal Nutrition and Adult Disease: Programming of Chronic Disease through Fetal Exposure to Undernutrition
- 11 beta-hydroxysteroid dehydrogenase.
- Metabolic conversion as a pre-receptor control mechanism for lipophilic hormones.
- A clinically relevant tapering protocol for Hydrocortisone Treatment in Newborn Animals
- 11 beta-hydroxysteroid dehydrogenase type 1 expression in 2S FAZA hepatoma cells is hormonally regulated: a model system for the study of hepatic glucocorticoid metabolism.
- Radioimmunoassay of cortisone in serum, urine, and saliva to assess the status of the cortisol-cortisone shuttle.
- 11β-Hydroxysteroid Dehydrogenase and the Syndrome of Apparent Mineralocorticoid Excess
- Immunohistochemical Localization of Type 1 11β-Hydroxysteroid Dehydrogenase in Human Tissues1
- Immunolocalization of 11β-Hydroxysteroid Dehydrogenase Types 1 and 2 in Rat Uterus: Variation Across the Estrous Cycle and Regulation by Estrogen and Progesterone.
- Obesity and corticosteroids: 11beta-hydroxysteroid type 1 as a cause and therapeutic target in metabolic disease.
- Effects of thyroid hormone (thyroxine) and testosterone on hepatic 11beta-hydroxysteroid dehydrogenase mRNA and activity in pubertal hypothyroid male rats.
- Validation and application of a highly specific and sensitive ELISA for the estimation of cortisone in saliva, urine and in vitro cell-culture media by using a novel antibody.
- Tissue specific effects of thyroid hormone on 11 beta-hydroxysteroid dehydrogenase gene expression.
- Quantitative Real-time PCR for the Measurement of 11β-HSD1 and 11β-HSD2 mRNA Levels in Tissues of Healthy Dogs
- Effect of growth hormone, insulin and dexamethasone on 11 beta-hydroxysteroid dehydrogenase activity on a primary culture of rat hepatocytes.
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