SignalP 6.0 predicts all five types of signal peptides using protein language models
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Summary
Signal peptides (SPs) are short amino acid sequences that control protein secretion and translocation in all living organisms and a new version of SignalP predicts all types of signal peptides.
- Type
- article
- Published
- 2022-01-03
- Cited by
- 2,422
- References
- 39
- Access
- Open access
- OpenAlex
- https://openalex.org/W4205192056
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:245653362
Keywords
Signal peptide, Secretion, Secretory protein, Peptide sequence, Protein sequencing
References
- A simple method for displaying the hydropathic character of a protein.
- Pathway specificity for a ΔpH‐dependent precursor thylakoid lumen protein is governed by a 'sec‐avoidance’ motif in the transfer peptide and a 'sec‐incompatible’ mature protein
- Membrane Proteases in the Bacterial Protein Secretion and Quality Control Pathway
- How many signal peptides are there in bacteria?
- Importance of the Anticodon Sequence in the Aminoacylation of tRNAs by Methionyl-tRNA Synthetase and by Valyl-tRNA Synthetase in an Archaebacterium*
- The signal peptide.
- Expediting topology data gathering for the TOPDB database
- Mutational and Bioinformatic Analysis of Haloarchaeal Lipobox-Containing Proteins
- Comparing two K-category assignments by a K-category correlation coefficient
- A general method applicable to the search for similarities in the amino acid sequence of two proteins.
- UniRef clusters: a comprehensive and scalable alternative for improving sequence similarity searches
- Lipoprotein biogenesis in Gram-positive bacteria: knowing when to hold 'em, knowing when to fold 'em.
- New and continuing developments at PROSITE
- Comparison of the predicted and observed secondary structure of T4 phage lysozyme.
- ScanProsite: detection of PROSITE signature matches and ProRule-associated functional and structural residues in proteins
- CD-HIT: accelerated for clustering the next-generation sequencing data
- The Tat Protein Export Pathway
- DeepSig: deep learning improves signal peptide detection in proteins
- A comprehensive review of signal peptides: Structure, roles, and applications.
- Archaeal cell surface biogenesis
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