Chemokine receptors (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology Database
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Summary
Chemokine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Chemokine Receptors [431, 430, 32]) comprise a large subfamily of 7TM proteins that bind one or more chemokines, a large family of small cytokines typically possessing chemotactic activity for leukocytes.
- Type
- article
- Published
- 2020-11-12
- Cited by
- 7
- References
- 468
- Access
- Open access
- OpenAlex
- https://openalex.org/W3101685330
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:228866940
Keywords
CCR1, Chemokine receptor, CCL7, CXC chemokine receptors, CCR3
References
- Eotaxin-2, a Novel CC Chemokine that Is Selective for the Chemokine Receptor CCR3, and Acts Like Eotaxin on Human Eosinophil and Basophil Leukocytes
- Cloning and Characterization of a Specific Receptor for the Novel CC Chemokine MIP-3α from Lung Dendritic Cells
- CXCR2 Regulates Respiratory Syncytial Virus-Induced Airway Hyperreactivity and Mucus Overproduction1
- Increased Expression of CCL20 in Human Inflammatory Bowel Disease
- Chemokine receptor CCR7 induces intracellular signaling that inhibits apoptosis of mature dendritic cells.
- CXCR3 and Its Ligands Participate in the Host Response to Bordetella bronchiseptica Infection of the Mouse Respiratory Tract but Are Not Required for Clearance of Bacteria from the Lung
- Mutational analysis of the extracellular disulphide bridges of the atypical chemokine receptor ACKR3/CXCR7 uncovers multiple binding and activation modes for its chemokine and endogenous non‐chemokine agonists
- Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets.
- Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression.
- Enhanced myeloid progenitor cell cycling and apoptosis in mice lacking the chemokine receptor, CCR2.
- HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor
- Chemokines: a new classification system and their role in immunity.
- TECK, an efficacious chemoattractant for human thymocytes, uses GPR-9-6/CCR9 as a specific receptor.
- Mast cell migratory response to interleukin-8 is mediated through interaction with chemokine receptor CXCR2/Interleukin-8RB.
- Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes.
- Characterization of two high affinity human interleukin-8 receptors.
- Molecular cloning of TER1, a chemokine receptor-like gene expressed by lymphoid tissues.
- Combinatorial Model of Chemokine Involvement in Glomerular Monocyte Recruitment: Role of CXC Chemokine Receptor 2 in Infiltration During Nephrotoxic Nephritis1
- A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo
- The CXC Chemokine Receptor 2, CXCR2, Is the Putative Receptor for ELR+ CXC Chemokine-Induced Angiogenic Activity1
Cited by
- Chemokine receptors differentially expressed by race category and molecular subtype in the breast cancer TCGA cohort
- G protein activation via chemokine (C-X-C motif) receptor 4 and α1b-adrenoceptor is ligand and heteromer-dependent
- Pharmacological characterization of a clinical candidate, TG-0054, a small molecule inverse agonist targeting CXCR4.
- The Chemokine (C-C Motif) Receptor 1 Antagonist BX471 Improves Fluid Resuscitation in Rat Models of Hemorrhagic Shock
- Activation of Chemokine (C‐C Motif) Receptor 1 Modulates α1B ‐Adrenoceptor and Arginine Vasopressin Receptor 1A Signaling and Function
- Fluid sparing effects of chemokine (C-C motif) receptor 1 and 2 antagonists during resuscitation from hemorrhagic shock in rat models
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