TECK, an efficacious chemoattractant for human thymocytes, uses GPR-9-6/CCR9 as a specific receptor.
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Summary
The data suggest that TECK/CCR9 interaction may play a pivotal role in T-cell migration in the thymus, and chemokines regulate leukocytes trafficking in normal and inflammation conditions.
- Type
- article
- Published
- 1999-10-01
- Cited by
- 106
- References
- 12
- OpenAlex
- https://openalex.org/W180496118
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12180913
Keywords
Chemokine receptor, Thymocyte, CC chemokine receptors, CCL25, Biology
References
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- Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK.
- Chemokines: signal lamps for trafficking of T and B cells for development and effector function
- Chemokines and T lymphocytes: more than an attraction.
- Cloning and Characterization of a Novel Promiscuous Human β-Chemokine Receptor D6*
- TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development.
- Cloning, Expression, and Chromosomal Mapping of a Novel Human CC-Chemokine Receptor (CCR10) That Displays High-Affinity Binding for MCP-1 and MCP-3
- T cell precursors in man and mice.
- Factors regulating stem cell recruitment to the fetal thymus.
- The thymic microenvironment.
- Flexible Programs of Chemokine Receptor Expression on Human Polarized T Helper 1 and 2 Lymphocytes
- Characterization of CKβ8 and CKβ8-1: Two Alternatively Spliced Forms of Human β-Chemokine, Chemoattractants for Neutrophils, Monocytes, and Lymphocytes, and Potent Agonists at CC Chemokine Receptor 1
Cited by
- A Tale from TGF-β Superfamily for Thymus Ontogeny and Function
- Role of the CC Chemokine receptor 9/TECK interaction in apoptosis
- Chemokine receptors: A brief overview
- Sélection centrale, survie et sélection périphérique des lymphocytes T ab CD8+
- Cloning and expression of cDNA for chemokine receptor 9 from Olive flounder, Paralichthys olivaceus
- Macrophage-Derived Chemokine and EBI1-Ligand Chemokine Attract Human Thymocytes in Different Stage of Development and Are Produced by Distinct Subsets of Medullary Epithelial Cells: Possible Implications for Negative Selection1
- Low thymic output in the 22q11.2 deletion syndrome measured by CCR9+CD45RA+ T cell counts and T cell receptor rearrangement excision circles
- Chemokines in immunity.
- Chemokine receptor signals: role in migration, invasion and cancer metastasis
- Characterization of thymic hyperplasia associated with autoimmune Myasthenia Gravis : role of the chemokines CXCL12 and CXCL13
- Expression of CC chemokine receptor 9 predicts poor prognosis in patients with lung adenocarcinoma
- Dendritic Cells Support Sequential Reprogramming of Chemoattractant Receptor Profiles During Naive to Effector T Cell Differentiation 1
- An IL-7 Fusion Protein That Shows Increased Thymopoietic Ability1
- Cutting Edge: Identification of a Novel Chemokine Receptor That Binds Dendritic Cell- and T Cell-Active Chemokines Including ELC, SLC, and TECK
- FoxP3+ T Cells Undergo Conventional First Switch to Lymphoid Tissue Homing Receptors in Thymus but Accelerated Second Switch to Nonlymphoid Tissue Homing Receptors in Secondary Lymphoid Tissues1
- Chemokines and lymphopoiesis in human thymus.
- Tracking thymocyte migration in situ.
- Trafficking of FoxP3+ regulatory T cells: myths and facts
- Role of Rho-ROCK signaling in MOLT4 cells metastasis induced by CCL25.
- Chemokines and their Receptors as Targets for the Treatment of COPD
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