SARS-CoV-2 vaccines in development
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Summary
The development of vaccines against SARS-CoV-2 is reviewed, including an overview of the development process, the different types of vaccine candidate, and data from animal studies as well as phase I and II clinical trials in humans.
- Type
- review
- Published
- 2020-09-23
- Cited by
- 1,881
- References
- 104
- Access
- Open access
- OpenAlex
- https://openalex.org/W3087924281
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:221887746
Keywords
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Virology, Coronavirus disease 2019 (COVID-19), 2019-20 coronavirus outbreak, Sars virus
References
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- Evaluation of Risks and Benefits Associated with Vaccination against Coronavirus Infections in Cats
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- A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge
- Improving pandemic H5N1 influenza vaccines by combining different vaccine platforms
- Granzyme B: Correlates with protection and enhanced CTL response to influenza vaccination in older adults
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- Influenza A and B viruses expressing altered NS1 proteins: A vaccine approach.
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- Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus
- Complete Genomic Sequence of Human Coronavirus OC43: Molecular Clock Analysis Suggests a Relatively Recent Zoonotic Coronavirus Transmission Event
- Antibodies against trimeric S glycoprotein protect hamsters against SARS-CoV challenge despite their capacity to mediate FcγRII-dependent entry into B cells in vitro
- Expression of Homing Receptors on IgA1 and IgA2 Plasmablasts in Blood Reflects Differential Distribution of IgA1 and IgA2 in Various Body Fluids
- Evaluation of modified vaccinia virus Ankara based recombinant SARS vaccine in ferrets
- Evaluation of the attenuation, immunogenicity, and efficacy of a live virus vaccine generated by codon-pair bias de-optimization of the 2009 pandemic H1N1 influenza virus, in ferrets
Cited by
- Understanding 'hybrid immunity': comparison and predictors of humoral immune responses to SARS-CoV-2 infection and COVID-19 vaccines.
- A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19
- A Single Immunization with Spike-Functionalized Ferritin Vaccines Elicits Neutralizing Antibody Responses against SARS-CoV-2 in Mice
- Immunogenicity of clinically relevant SARS-CoV-2 vaccines in nonhuman primates and humans
- Single-component, self-assembling, protein nanoparticles presenting the receptor binding domain and stabilized spike as SARS-CoV-2 vaccine candidates
- Antisense oligonucleotides target a nearly invariant structural element from the SARS-CoV-2 genome and drive RNA degradation
- Client Engineering of XVA in Crisis and Normality: Restructuring, Mandatory Breaks and Resets
- Age-targeted dose allocation can halve COVID-19 vaccine requirements
- All eyes on a hurdle race for a SARS-CoV-2 vaccine
- Outpatient Management of COVID-19: Rapid Evidence Review.
- Flattening the Risk: Pre-Exposure Prophylaxis for COVID-19
- COVID-19: Rethinking the Lockdown Groupthink
- Structural impact on SARS-CoV-2 spike protein by D614G substitution
- Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine
- Viral surface geometry shapes influenza and coronavirus spike evolution through antibody pressure
- T cell immunity to SARS-CoV-2 following natural infection and vaccination
- Next-Generation Pertussis Vaccines Based on the Induction of Protective T Cells in the Respiratory Tract
- Is there a role for childhood vaccination against COVID‐19?
- Biomimetic Nanomaterial Strategies for Virus Targeting: Antiviral Therapies and Vaccines
- Viral Immunity and Vaccines in Hematologic Malignancies: Implications for COVID-19
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