Age-targeted dose allocation can halve COVID-19 vaccine requirements
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Summary
An age-structured mathematical model is used to investigate the benefits of optimizing age-specific dose allocation to suppress the transmission, morbidity and mortality of SARS-CoV-2 and the associated disease, COVID-19 and shows that optimizing the allocation of vaccine doses can more than double their effectiveness.
- Type
- preprint
- Published
- 2020-10-11
- Cited by
- 29
- References
- 30
- Access
- Open access
- OpenAlex
- https://openalex.org/W3091902263
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:225136781
Keywords
Herd immunity, Transmission (telecommunications), Disease, Coronavirus disease 2019 (COVID-19), Medicine
References
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- The COVID-19 vaccine development landscape
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- Projecting contact matrices in 177 geographical regions: An update and comparison with empirical data for the COVID-19 era
- Vaccine optimization for COVID-19: who to vaccinate first?
Cited by
- The risk for a new COVID-19 wave and how it depends on R0, the current immunity level and current restrictions
- A Net Benefit Approach for the Optimal Allocation of a COVID-19 Vaccine
- Understanding COVID-19 Dynamics and the Effects of Interventions in the Philippines: A Mathematical Modelling Study
- Vaccination strategies for minimizing loss of life in Covid-19 in a Europe lacking vaccines
- Optimal Allocation of the Limited COVID-19 Vaccine Supply in South Korea
- Minimizing loss of life in Covid-19 in a 100 day period in the U.S.A. by age-tailored dosing and distribution of a limited vaccine supply
- Minimizing Loss of Life in COVID-19 in a 100 Day Period in the U.S.A. by Personalized-Dose Vaccination
- Personalized-Dose COVID-19 Vaccination in a Wave of Virus Variants of Concern: Trading Individual Efficacy for Societal Benefit
- How will mass-vaccination change COVID-19 lockdown requirements in Australia?
- Multi-generational SIR modeling: Determination of parameters, epidemiological forecasting and age-dependent vaccination policies
- Despite vaccination, China needs non-pharmaceutical interventions to prevent widespread outbreaks of COVID-19 in 2021
- Vaccine Effects on Susceptibility and Symptomatology Can Change the Optimal Allocation of COVID-19 Vaccines: South Korea as an Example
- Models of COVID-19 vaccine prioritisation: a systematic literature search and narrative review
- Understanding COVID-19 dynamics and the effects of interventions in the Philippines: A mathematical modelling study
- Vaccination is Australia's most important COVID-19 public health action, even though herd immunity is unlikely
- Modelling direct and herd protection effects of vaccination against the SARS‐CoV‐2 Delta variant in Australia
- The role of childrens’ vaccination for COVID-19—Pareto-optimal allocations of vaccines
- Inferring the reproduction number using the renewal equation in heterogeneous epidemics
- Mathematical modelling of vaccination rollout and NPIs lifting on COVID-19 transmission with VOC: a case study in Toronto, Canada
- Optimal vaccination at high reproductive numbers: sharp transitions and counterintuitive allocations
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