Engineered Hydrogels for Brain Tumor Culture and Therapy
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Summary
Through further development, hydrogels can serve as a reliable option for in vitro modeling and treatment of brain tumors for translational medicine and should be considered for drug delivery and co-administration with other therapies.
- Type
- article
- Published
- 2020-06-30
- Cited by
- 40
- References
- 161
- Access
- Open access
- OpenAlex
- https://openalex.org/W3039134434
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:220509719
Keywords
Self-healing hydrogels, Extracellular matrix, Drug delivery, Brain tumor, Neuroscience
References
- Designing Cell-Compatible Hydrogels for Biomedical Applications
- CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011.
- Three-Dimensional Culture Systems in Cancer Research: Focus on Tumor Spheroid Model
- Hyaluronic-Acid Based Hydrogels for 3-Dimensional Culture of Patient-Derived Glioblastoma Cells.
- Stereotaxic implantation of 5‐fluorouracil‐releasing microspheres in malignant glioma
- Generation of 3-D glioblastoma-vascular niche using 3-D bioprinting
- Structural and functional features of central nervous system lymphatics
- Temozolomide-loaded photopolymerizable PEG-DMA-based hydrogel for the treatment of glioblastoma.
- Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor.
- Glioma cell migration on three-dimensional nanofiber scaffolds is regulated by substrate topography and abolished by inhibition of STAT3 signaling.
- Challenges and Opportunities for Tissue-Engineering Polarized Epithelium
- Revisiting the concept of CNS immune privilege
- Bioprinting for cancer research.
- Mimicking white matter tract topography using core–shell electrospun nanofibers to examine migration of malignant brain tumors
- Use of Gliadel (BCNU) Wafer in the Surgical Treatment of Malignant Glioma: A 10-Year Institutional Experience
- Hydrogel Matrix Entrapping PLGA-Paclitaxel Microspheres: Drug Delivery with Near Zero-Order Release and Implantability Advantages for Malignant Brain Tumour Chemotherapy
- Glioma cells escaped from cytotoxicity of temozolomide and vincristine by communicating with human astrocytes
- Overcoming the blood-brain tumor barrier for effective glioblastoma treatment.
- Treatment of rat brain tumors using sustained-release of camptothecin from poly(lactic-co-glycolic acid) microspheres in a thermoreversible hydrogel.
- Tumour vasculogenic mimicry is associated with poor prognosis of human cancer patients: a systemic review and meta-analysis.
Cited by
- Engineering in vitro human tissue models through bio-design and manufacturing
- Biocompatible Copolymer Formulations to Treat Glioblastoma Multiforme.
- Electrospinning of a sandwich-structured membrane with sustained release capability and long-term anti-inflammatory effects for dental pulp regeneration
- A dual-layer cell-laden tubular scaffold for bile duct regeneration
- High-Throughput FRAP Analysis of Solute Diffusion in Hydrogels
- A review of recent progress toward the efficient separation of circulating tumor cells via micro‐/nanostructured microfluidic chips
- Vascularizing the brain in vitro
- Fusion between Glioma Stem Cells and Mesenchymal Stem Cells Promotes Malignant Progression in 3D-Bioprinted Models.
- A Silk Fibroin Methacryloyl-Modified Hydrogel Promoting Cell Adhesion for Customized 3D Cell-Laden Structures
- Development of conductive hydrogels: from design mechanisms to frontier applications
- Micro-Nanocarriers Based Drug Delivery Technology for Blood-Brain Barrier Crossing and Brain Tumor Targeting Therapy.
- Mechanical stretching of 3D hydrogels for neural stem cell differentiation
- Thermo-sensitive Sacrificial Microsphere-based Bioink for Centimeter-scale Tissue with Angiogenesis
- Emerging Materials, Wearables, and Diagnostic Advancements in Therapeutic Treatment of Brain Diseases
- Hybrid biofabrication of neurosecretory structures as a model for neurosecretion
- Evaluation of the Effect of Fibroblasts on Melanoma Metastasis Using a Biomimetic Co-Culture Model.
- Long-Acting Therapeutic Delivery Systems for the Treatment of Gliomas.
- Structurally decoupled stiffness and solute transport in multi-arm poly (ethylene glycol) hydrogels
- 3D printing of stimuli-responsive hydrogel materials: Literature review and emerging applications
- The role of hydrogels in the management of brain tumours: a narrative review
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