GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes

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Summary

A practical implementation of the polyploid-aware mixture model that quickly and accurately infers genome properties across thousands of simulated and several real datasets spanning a broad range of complexity is described and evaluated.

Type
article
Published
2020-03-18
Cited by
2,437
References
40
Access
Open access

Keywords

Polyploid, Genome, Ploidy, Loss of heterozygosity, Biology

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