Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan
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Summary
Binformatics analysis on a virus genome from a patient with 2019-nCoV infection and compared it with other related coronavirus genomes provide the basis for starting further studies on the pathogenesis, and optimizing the design of diagnostic, antiviral and vaccination strategies for this emerging infection.
- Type
- article
- Published
- 2020-01-01
- Cited by
- 2,736
- References
- 28
- Access
- Open access
- OpenAlex
- https://openalex.org/W3003464757
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:210933971
Keywords
Coronavirus, Betacoronavirus, Biology, Genome, Virology
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- Over-expression of severe acute respiratory syndrome coronavirus 3b protein induces both apoptosis and necrosis in Vero E6 cells
- Severe Acute Respiratory Syndrome Coronavirus as an Agent of Emerging and Reemerging Infection
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- Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from Greater Horseshoe Bats through Recombination
- MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2
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- A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike
- The PSIPRED Protein Analysis Workbench: 20 years on
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- SARS-CoV-2 Variants, Current Vaccines and Therapeutic Implications for COVID-19
- Should remdesivir be recommended in France in the early stage of COVID-19
- Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag
- An emerging coronavirus causing pneumonia outbreak in Wuhan, China: calling for developing therapeutic and prophylactic strategies
- The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes
- SNV Reoccurrence in Multiple Regions in the Genome of 2019-nCoV
- ACE2 expression by colonic epithelial cells is associated with viral infection, immunity, and energy metabolism
- The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
- Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses
- RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak
- Consistent Detection of 2019 Novel Coronavirus in Saliva
- Structural genomics and interactomics of 2019 Wuhan novel coronavirus, 2019-nCoV, indicate evolutionary conserved functional regions of viral proteins
- Epidemiological and clinical features of the 2019 novel coronavirus outbreak in China
- Glycopeptide antibiotic teicoplanin inhibits cell entry of SARS-CoV-2 by suppressing the proteolytic activity of cathepsin L
- Potential interventions for novel coronavirus in China: A systematic review
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges
- Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
- Enteric involvement of coronaviruses: is faecal–oral transmission of SARS-CoV-2 possible?
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