Metabolic regulation of epigenetic remodeling in immune cells
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Summary
Recent studies are reviewed that demonstrate shifts in metabolic state can orchestrate immune cell functions through its impact on epigenetic remodeling, and the microenvironment can exert its influence on immune cells through the metabolic regulation of epigenetics.
- Type
- review
- Published
- 2020-01-15
- Cited by
- 50
- References
- 67
- Access
- Open access
- OpenAlex
- https://openalex.org/W2999641105
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:210715581
Keywords
Immune system, Epigenetics, Biology, Reprogramming, Immunity
References
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- Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
- Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction
- Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation
- Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation
- Metabolic regulation of histone post-translational modifications
- Memory CD8(+) T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function.
- Gut Microbial Metabolites Fuel Host Antibody Responses
Cited by
- Metformin: Sentinel of the Epigenetic Landscapes That Underlie Cell Fate and Identity
- CALCIUM REGULATION OF T CELL METABOLISM
- Nutritional status, diet and viral respiratory infections: perspectives for severe acute respiratory syndrome coronavirus 2
- The Complex Integration of T cell Metabolism and Immunotherapy
- Metabolites in the Tumor Microenvironment Reprogram Functions of Immune Effector Cells Through Epigenetic Modifications
- Irg1-itaconate axis protects against acute kidney injury via activation of Nrf2.
- PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway
- LPS-induced lipid alterations in microglia revealed by MALDI mass spectrometry-based cell fingerprinting in neuroinflammation studies
- A matter of time: Temporal structure and functional relevance of macrophage metabolic rewiring
- Epigenetic regulation of inflammation: The metabolomics connection.
- Crosstalk between metabolic reprogramming and epigenetics in cancer: updates on mechanisms and therapeutic opportunities
- The regulation of totipotency transcription: Perspective from in vitro and in vivo totipotency
- Metabolic control of innate lymphoid cells in health and disease
- Epigenetic regulation of macrophage polarization in wound healing
- Innate Immune Memory in Macrophages
- Metabolic alterations of the immune system in the pathogenesis of autoimmune diseases
- Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis
- Metabolic switches during development and regeneration.
- Cardiac Macrophage Metabolism in Health and Disease
- Polyphenols: immunonutrients tipping the balance of immunometabolism in chronic diseases
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