The role of deubiquitinating enzymes in gastric cancer
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Summary
The literature investigating the association between DUBs and GC pathophysiology was analyzed and critically appraised, and generally, Dubs were upregulated in gastric cancer.
- Type
- review
- Published
- 2019-11-07
- Cited by
- 33
- References
- 139
- Access
- Open access
- OpenAlex
- https://openalex.org/W2984789292
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:209229515
Keywords
Deubiquitinating enzyme, Cancer, Oncogene, Molecular medicine, Cell cycle
References
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- Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling
- Suppression of CSN5 promotes the apoptosis of gastric cancer cells through regulating p53-related apoptotic pathways.
- Exploring the association between genetic variation in the SUMO isopeptidase gene USPL1 and breast cancer through integration of data from the population‐based GENICA study and external genetic databases
- Characterization of novel yeast RAD6 (UBC2) ubiquitin-conjugating enzyme mutants constructed by charge-to-alanine scanning mutagenesis
- Monocyte Chemotactic Protein-induced Protein 1 and 4 Form a Complex but Act Independently in Regulation of Interleukin-6 mRNA Degradation*
- Noncanonical regulation of alkylation damage resistance by the OTUD4 deubiquitinase
- Mechanisms underlying ubiquitination.
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- The de-ubiquitinase UCHL1 promotes gastric cancer metastasis via the Akt and Erk1/2 pathways
- Progress in epigenetic histone modification analysis by mass spectrometry for clinical investigations
- Regulation of p53 stability and function by the deubiquitinating enzyme USP42
- Over-expression of genes and proteins of ubiquitin specific peptidases (USPs) and proteasome subunits (PSs) in breast cancer tissue observed by the methods of RFDD-PCR and proteomics
- Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity.
- CSN-associated USP48 confers stability to nuclear NF-κB/RelA by trimming K48-linked Ub-chains.
- The Co-expression of USP22 and BMI-1 May Promote Cancer Progression and Predict Therapy Failure in Gastric Carcinoma
- Expression of Eukaryotic Initiation Factor 3f Is Associated with Prognosis in Gastric Carcinomas
- Kinetic and mechanistic studies on the hydrolysis of ubiquitin C-terminal 7-amido-4-methylcoumarin by deubiquitinating enzymes.
- Characteristics of gastric cancer in Asia.
- Ubiquitin C-terminal hydrolase-L1 is a key regulator of tumor cell invasion and metastasis
Cited by
- Ubiquitin‐specific protease 3 overexpression promotes gastric carcinogenesis and is predictive of poor patient prognosis
- Activation and selectivity of OTUB-1 and OTUB-2 deubiquitinylases
- Regulation of Wnt Signaling through Ubiquitination and Deubiquitination in Cancers
- USP43 directly regulates ZEB1 protein, mediating proliferation and metastasis of colorectal cancer
- The post translational modification of key regulators of ATR signaling in DNA replication
- Interactions between SARS coronavirus 2 papain‐like protease and immune system: A potential drug target for the treatment of COVID‐19
- Ubiquitin-Specific Proteases: Players in Cancer Cellular Processes
- Low EBI3 Expression Promotes the Malignant Degree of Gastric Cancer
- The role of ubiquitination and deubiquitination in tumor invasion and metastasis
- USP40 deubiquitinates HINT1 and stabilizes p53 in podocyte damage.
- Exploiting the ubiquitin system in myeloid malignancies. From basic research to drug discovery in MDS and AML.
- Molecular markers in cancer.
- Degradome-focused RNA interference screens to identify proteases important for breast cancer cell growth
- Ubiquitin-Specific Proteases (USPs) and Metabolic Disorders
- Ubiquitin-Specific Protease 43 Impacts Pancreatic Ductal Adenocarcinoma Prognosis by Altering Its Proliferation and Infiltration of Surrounding Immune Cells
- Disrupting of family with sequence similarity 105, member A (Fam105a) deteriorates pancreatic β-cell physiology and insulin secretion in INS-1 cells.
- USP15-USP7 Axis and UBE2T Differential Expression May Predict Pathogenesis and Poor Prognosis in De Novo Myelodysplastic Neoplasm
- Spotlights on ubiquitin-specific protease 12 (USP12) in diseases: from multifaceted roles to pathophysiological mechanisms
- Isoform alterations in the ubiquitination machinery impacting gastrointestinal malignancies
- An Overview of the Deubiquitinase USP53: A Promising Diagnostic Marker and Therapeutic Target
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