Dopamine negatively modulates the NCA ion channels in C. elegans
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Summary
Dopamine signaling to activity of the NCA channels through G protein signaling pathways is identified and it is demonstrated that dopamine, through DOP-3, negatively regulates NCA activity.
- Type
- article
- Published
- 2016-12-30
- Cited by
- 27
- References
- 137
- Access
- Open access
- OpenAlex
- https://openalex.org/W2952483740
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25969437
Keywords
Heterotrimeric G protein, Biology, Cell biology, G protein, Dopamine
References
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Cited by
- Effects of apomorphine, a dopamine agonist, on Daphnia magna: Imaging of swimming track density as a novel tool in the assessment of swimming activity.
- The ERK MAPK pathway modulates Gq-dependent locomotion in Caenorhabditis elegans
- Modulation of Gq-Rho Signaling by the ERK MAPK Pathway Controls Locomotion in Caenorhabditis elegans
- Activation of RHO-1 in cholinergic motor neurons competes with dopamine signalling to control locomotion
- Gi/o protein-coupled receptors in dopamine neurons inhibit the sodium leak channel NALCN
- Corticostriatal synaptic weight evolution in a two-alternative forced choice task
- Risk Factor Genes in Patients with Dystonia: A Comprehensive Review
- The NALCN regulator UNC-80 functions in a subset of interneurons to affect C. elegans avoidance response to the plant hormone methyl salicylate
- Presynaptic Gαo (GOA-1) signaling depresses command neuron excitability to allow for stretch-dependent modulation of egg-laying behavior in C. elegans
- Novel pharmacological modulation of dystonic phenotypes caused by a gain-of-function mutation in the Na+ leak-current channel
- Drebrin-like protein regulates body bending of C. elegans via suppression of NCA cation leak channels
- Normal Ethanol Sensitivity and Rapid Tolerance Require the G Protein Receptor Kinase 2 in Ellipsoid Body Neurons in Drosophila
- Dopamine receptor DOP-1 engages a sleep pathway to modulate swimming in C. elegans
- Neuronal Mechanisms Underlying Opioid Induced Respiratory Depression: Our Current Understanding.
- Na+ leak-current channel (NALCN) at the junction of motor and neuropsychiatric symptoms in Parkinson’s disease
- Presynaptic Gαo (GOA-1) signals to depress command neuron excitability and allow stretch-dependent modulation of egg laying in Caenorhabditis elegans.
- Differential modulation of C. elegans motor behavior by NALCN and two-pore domain potassium channels
- G Protein-Coupled Receptor Kinase-2 (GRK-2) controls exploration through neuropeptide signaling in Caenorhabditis elegans
- Systematic creation and phenotyping of Mendelian disease models in C. elegans: towards large-scale drug repurposing
- High-throughput tracking enables systematic phenotyping and drug repurposing in C. elegans disease models
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