Exosomes: biogenesis, biologic function and clinical potential
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Summary
The potential use of exosomes as valuable diagnostic and prognostic biomarkers for their cell-lineage and state-specific contents, and possibilities as therapeutic vehicles for drug and gene delivery are focused on.
- Type
- review
- Published
- 2019-02-15
- Cited by
- 1,838
- References
- 156
- Access
- Open access
- OpenAlex
- https://openalex.org/W2931418311
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:62881043
Keywords
Microvesicles, Exosome, Nanocarriers, Biogenesis, Reprogramming
References
- Exosome-formed synthetic microRNA-143 is transferred to osteosarcoma cells and inhibits their migration.
- Exosomes as Drug Delivery Vehicles for Parkinson’s Disease Therapy
- Exosomes in the nose induce immune cell trafficking and harbour an altered protein cargo in chronic airway inflammation
- Extracellular vesicle associated long non-coding RNAs functionally enhance cell viability
- Exosomes From Adipose-derived Mesenchymal Stem Cells Protect the Myocardium Against Ischemia/Reperfusion Injury Through Wnt/β-Catenin Signaling Pathway
- Sphingolipid metabolism and neutral sphingomyelinases
- Integrated isolation and quantitative analysis of exosome shuttled proteins and nucleic acids using immunocapture approaches.
- Using exosomes, naturally-equipped nanocarriers, for drug delivery
- Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial
- CD73 expression on extracellular vesicles derived from CD4+CD25+Foxp3+ T cells contributes to their regulatory function
- Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis
- Clinical impact of serum exosomal microRNA‐21 as a clinical biomarker in human esophageal squamous cell carcinoma
- Proteomic Analysis of Dendritic Cell-Derived Exosomes: A Secreted Subcellular Compartment Distinct from Apoptotic Vesicles1
- Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids
- Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes).
- Proteomics of extracellular vesicles: Exosomes and ectosomes.
- MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic disease.
- Exosomes as immunotheranostic nanoparticles.
- Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: a new approach for drug delivery.
- Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications.
Cited by
- Myosin Va and spermine synthase: partners in exosome transport
- Ultrasound Facilitates Naturally Equipped Exosomes Derived from Macrophages and Blood Serum for Orthotopic Glioma Treatment.
- Cell-Free Nucleic Acids and their Emerging Role in the Pathogenesis and Clinical Management of Inflammatory Bowel Disease
- Macrophage Rewiring by Nutrient Associated PI3K Dependent Pathways
- Extracellular Vesicles: A Possible Link between HIV and Alzheimer’s Disease-Like Pathology in HIV Subjects?
- A Brief Review about the Role of Nanomaterials, Mineral-Organic Nanoparticles, and Extra-Bone Calcification in Promoting Carcinogenesis and Tumor Progression
- New insights into the immunomodulatory role of exosomes in cardiovascular disease.
- Exosome Treatment Enhances Anti-Inflammatory M2 Macrophages and Reduces Inflammation-Induced Pyroptosis in Doxorubicin-Induced Cardiomyopathy
- Translational Application of Circulating DNA in Oncology: Review of the Last Decades Achievements
- Extracellular Vesicles as Natural, Safe and Efficient Drug Delivery Systems
- Exosomes: Current Use and Future Applications.
- Macrophage-Derived Extracellular Vesicles as Drug Delivery Systems for Triple Negative Breast Cancer (TNBC) Therapy
- Exosomes facilitate chemoresistance in gastric cancer: Future challenges and openings
- Intraluminal vesicles of binucleate trophoblast cell granules are a possible source of placental exosomes in ruminants.
- Engineering of Exosomes to Target Cancer Metastasis
- Developments in predictive biomarkers for hepatocellular carcinoma therapy
- Apoptotic cell-derived exosomes: messages from dying cells
- Lipidomic characterization of exosomes isolated from human plasma using various mass spectrometry techniques.
- A Comprehensive Picture of Extracellular Vesicles and Their Contents. Molecular Transfer to Cancer Cells
- Engineered Tumor-Derived Extracellular Vesicles: Potentials in Cancer Immunotherapy
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