Association between insulin resistance and the development of cardiovascular disease
Explore this paper's citation graph
Summary
It can be concluded that insulin resistance in the myocardium generates damage by at least three different mechanisms: (1) signal transduction alteration, (2) impaired regulation of substrate metabolism, and (3) altered delivery of substrates to theMyocardium.
- Type
- review
- Published
- 2018-08-31
- Cited by
- 1,878
- References
- 183
- Access
- Open access
- OpenAlex
- https://openalex.org/W2888814360
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:52141795
Keywords
Insulin resistance, Internal medicine, Endocrinology, Insulin, Dyslipidemia
References
- Effect of insulin resistance, dyslipidemia, and intra-abdominal adiposity on the development of cardiovascular disease and diabetes mellitus.
- Regulation of glucose transporter translocation in health and diabetes.
- Epicardial and Perivascular Adipose Tissues and Their Influence on Cardiovascular Disease: Basic Mechanisms and Clinical Associations
- Endothelial dysfunction in conduit arteries and in microcirculation. Novel therapeutic approaches.
- Sitagliptin improved glucose assimilation in detriment of fatty-acid utilization in experimental type-II diabetes: role of GLP-1 isoforms in Glut4 receptor trafficking
- Effect of insulin on ketone body clearance studied by a ketone body “clamp” technique in normal man
- Insulin Resistance and Heart Failure: Molecular Mechanisms
- Insulin and insulin resistance.
- Effect of valsartan on the incidence of diabetes and cardiovascular events.
- The hormone resistin links obesity to diabetes
- Disruption of IRS-2 causes type 2 diabetes in mice
- Improved energy homeostasis of the heart in the metabolic state of exercise.
- Glutathione metabolism and its implications for health.
- Pathophysiology of insulin resistance in human disease.
- Fatty Acids Activate Transcription of the Muscle Carnitine Palmitoyltransferase I Gene in Cardiac Myocytes via the Peroxisome Proliferator-activated Receptor α*
- Metabolic syndrome and risk factors for cardiovascular disease in obese children: the relationship with insulin resistance (HOMA-IR).
- Insulin signalling mechanisms for triacylglycerol storage
- Cardiac Metabolism and Its Interactions with Contraction, Growth, and Survival of the Cardiomyocte
- Lipid Metabolism and Toxicity in the Heart
- Nitric oxide and vascular insulin resistance
Cited by
- Dietary Restrictions and Nutrition in the Prevention and Treatment of Cardiovascular Disease.
- Dyslipidemia and cardiovascular disease risk factors in patients with type 1 diabetes: A single-center experience
- The Relationship between Hepatic Steatosis, inflammation and insulin Resistance in type 2 Diabetes with Metabolic Imbalance
- Body mass index mediates the association between meat intake and insulin sensitivity.
- ACE2 polymorphisms associated with cardiovascular risk in Uygurs with type 2 diabetes mellitus
- Effects of Brassica oleracea extract on impaired glucose and lipid homeostasis in high-fat diet-induced obese mice
- Targeting the Zinc Transporter ZIP7 in the Treatment of Insulin Resistance and Type 2 Diabetes
- The Association between Mineral and Trace Element Concentrations in Hair and the 10-Year Risk of Atherosclerotic Cardiovascular Disease in Healthy Community-Dwelling Elderly Individuals
- Soy husk extract improves physical and biochemical parameters of obese-diabetic rats through the regulation of PPARγ expression.
- Adiponectin and insulin resistance are related to restenosis and overall new PCI in subjects with normal glucose tolerance: the prospective AIRE Study
- Fish oil protects against corn oil-induced cardiac insulin resistance and left ventricular dysfunction in rats via upregulation of PPAR-β/γ and inhibition of diacylglycerol/PCK axis activation
- Antidiabetic potential of gallic acid from Emblica officinalis: Improved glucose transporters and insulin sensitivity through PPAR-γ and Akt signaling.
- Saturated fatty acid stimulates production of extracellular vesicles by renal tubular epithelial cells
- Cocoa Shell Aqueous Phenolic Extract Preserves Mitochondrial Function and Insulin Sensitivity by Attenuating Inflammation between Macrophages and Adipocytes In Vitro.
- Changes in insulin resistance mediate the associations between phthalate exposure and metabolic syndrome.
- Association between waist circumference and waist-to-height ratio with insulin resistance biomarkers in normal-weight adults working in a private educational institution.
- Nomogram Based on Cytokines for Cardiovascular Diseases in Xinjiang Kazakhs
- Consecutive days of exercise decrease insulin response more than a single exercise session in healthy, inactive men
- Elevated fasting insulin is associated with cardiovascular and metabolic risk in women with polycystic ovary syndrome.
- The role of the triglyceride (triacylglycerol) glucose index in the development of cardiovascular events: a retrospective cohort analysis
Related papers
- Prevalence and pattern of diabetic dyslipidemia in Indian type 2 diabetic patients
- Analysis of dyslipidemia for staffs at government departments of some towns in Wuling mountains
- Cross-sectional study of pattern of Dyslipidemia and Prevalence of Atherogenic Diabetic Dyslipidemia in newly detected Diabetic patients
- Is the effect of high fat diet on lipid and carbohydrate metabolism related to inflammation?
- Regulation of glucose/lipid metabolism and insulin sensitivity by interleukin-4
- Research Progress of the Effect of Berberine on the Metabolism of Glucose and Lipids
- The effect of androgens and related substances on carbohydrate metabolism, lipid metabolism and diabetes mellitus
- The effects of HIV protease inhibitors on carbohydrate and lipid metabolism
- The Interrelationships of Carbohydrate and Lipid Metabolism